Universität zu Köln

Soresi, Simona, Zeriouh, Mohamed, Sabashnikov, Anton ORCID: 0000-0002-6289-1035, Mc Dermott, Grainne, Weymann, Alexander, Wippermann, Jens, Wahlers, Thorsten, Reed, Anna, Carby, Martin, Simon, Andre R. and Popov, Aron-Frederik ORCID: 0000-0003-4226-3004 (2016). GORD symptoms in lung transplantation: how efficient is the reflux symptom index questionnaire compared to the esophageal impedance test? Clin. Transplant., 30 (1). S. 44 - 52. HOBOKEN: WILEY-BLACKWELL. ISSN 1399-0012

Full text not available from this repository.

Abstract

ObjectiveAs Gastroesophageal reflux disease (GORD) affects long-term survival in lung transplant recipients, the aim of this observational prospective study was to analyze the efficacy of The Reflux Symptom Index Questionnaire (RSI) compared to the esophageal impedance test. MethodsBoth esophageal impedance studies and RSI questionnaire were routinely performed in all patients who had completed rehabilitation following lung transplantation from June 2013 till March 2014. RSI generates a score of between zero and forty-five, taking into account any symptoms within four wk of the questionnaire. Our analysis considered RSI score cut-offs of 10 and 13 indicating significance of reflux. ResultsOut of 84 patients, 50 (59.5%) had evidence of GORD detected by impedance studies, whereas only 33 (39.2%) and 22 (26.2%) had RSI >10 and 13, respectively. An elevated RSI was not found to be associated with positive impedance studies using a score of either 10 or 13 (p = 0.127 and p = 0.142, respectively); 32.1% (n = 27) and 40.5% (n = 34) were found to have negative RSI and positive impedance test using 10 or 13 as cut-off, respectively. ConclusionRSI Score is an unreliable predictor of GORD among lung transplant recipients. The authors therefore recommend the routine use of impedance testing in post-transplant patients.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Soresi, Simona UNSPECIFIED UNSPECIFIED UNSPECIFIED Zeriouh, Mohamed UNSPECIFIED UNSPECIFIED UNSPECIFIED Sabashnikov, Anton UNSPECIFIED orcid.org/0000-0002-6289-1035 UNSPECIFIED Mc Dermott, Grainne UNSPECIFIED UNSPECIFIED UNSPECIFIED Weymann, Alexander UNSPECIFIED UNSPECIFIED UNSPECIFIED Wippermann, Jens UNSPECIFIED UNSPECIFIED UNSPECIFIED Wahlers, Thorsten UNSPECIFIED UNSPECIFIED UNSPECIFIED Reed, Anna UNSPECIFIED UNSPECIFIED UNSPECIFIED Carby, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Simon, Andre R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Popov, Aron-Frederik UNSPECIFIED orcid.org/0000-0003-4226-3004 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-291844
DOI:	10.1111/ctr.12656
Journal or Publication Title:	Clin. Transplant.
Volume:	30
Number:	1
Page Range:	S. 44 - 52
Date:	2016
Publisher:	WILEY-BLACKWELL
Place of Publication:	HOBOKEN
ISSN:	1399-0012
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language GASTROESOPHAGEAL-REFLUX; BRONCHIOLITIS OBLITERANS; DISEASE; ASPIRATION; FUNDOPLICATION; FIBROSIS Multiple languages Surgery; Transplantation Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/29184