Universität zu Köln

Hein, Markus, Chobanyan-Juergens, Kristine, Tegtbur, Uwe, Engeli, Stefan, Jordan, Jens and Haufe, Sven . Effect of normobaric hypoxic exercise on blood pressure in old individuals. Eur. J. Appl. Physiol.. NEW YORK: SPRINGER. ISSN 1439-6327

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Abstract

Purpose To test the hypothesis that the combination of endurance training and hypoxia leads to greater improvements in resting and exercise blood pressure in old sedentary individuals compared to endurance training only. Methods We randomly assigned 29 old overweight participants (age: 62 +/- 6 years, body mass index (BMI): 28.5 +/- 0.5 kg/m(2), 52% men) to single blind 8-week bicycle exercise in hypoxia (fraction of inspired oxygen (FIO2) = 0.15) or normoxia (FIO2 = 0.21). Brachial blood pressure was measured at rest, during maximal incremental exercise testing, and during a 30 min constant work rate test, at baseline and after the training period. Results Work rate, heart rate and perceived exertion during training were similar in both groups, with lower oxygen saturation for participants exercising under hypoxia (88.7 +/- 1.5 vs. 96.2 +/- 1.2%, t(27) = - 13.04, p < 0.001, |g|= 4.85). Office blood pressure and blood pressure during incremental exercise tests did not change significantly in either group after the training program. Systolic blood pressure during the constant work rate test was reduced after training in hypoxia (160 +/- 18 vs. 151 +/- 14 mmHg, t(13) = 2.44 p < 0.05, |d|= 0.55) but not normoxia (154 +/- 22 vs. 150 +/- 16 mmHg, t(14) = 0.75, p = 0.46, |d|= 0.18) with no difference between groups over time (F = 0.08, p = 0.77, eta(2) = 0.01). Conclusion In old individuals hypoxia in addition to exercise does not have superior effects on office or exercise blood pressure compared to training in normoxia.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Hein, Markus UNSPECIFIED UNSPECIFIED UNSPECIFIED Chobanyan-Juergens, Kristine UNSPECIFIED UNSPECIFIED UNSPECIFIED Tegtbur, Uwe UNSPECIFIED UNSPECIFIED UNSPECIFIED Engeli, Stefan UNSPECIFIED UNSPECIFIED UNSPECIFIED Jordan, Jens UNSPECIFIED UNSPECIFIED UNSPECIFIED Haufe, Sven UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-307497
DOI:	10.1007/s00421-020-04572-6
Journal or Publication Title:	Eur. J. Appl. Physiol.
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1439-6327
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language INTERMITTENT HYPOXIA; NITRIC-OXIDE; ENDOTHELIAL FUNCTION; RISK-FACTORS; SKELETAL-MUSCLE; SLEEP-APNEA; MECHANISMS; ALTITUDE; MODERATE; THERAPY Multiple languages Physiology; Sport Sciences Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/30749