Psychogios, Marios-Nikos, Sporns, Peter B., Ospel, Johanna, Katsanos, Aristeidis H., Kabiri, Reza, Flottmann, Fabian A., Menon, Bijoy K., Horn, Mackenzie, Liebeskind, David S., Honda, Tristan, Ribo, Marc ORCID: 0000-0001-9242-043X, Ruiz, Manuel Requena, Kabbasch, Christoph, Lichtenstein, Thorsten, Maurer, Christoph J., Berlis, Ansgar, Hellstern, Victoria, Henkes, Hans, Moehlenbruch, Markus A., Seker, Fatih, Ernst, Marielle S., Liman, Jan, Tsivgoulis, Georgios and Brehm, Alex . Automated Perfusion Calculations vs. Visual Scoring of Collaterals and CBV-ASPECTS Has the Machine Surpassed the Eye? Clin. Neuroradiol.. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1869-1447

Full text not available from this repository.

Abstract

Purpose Use of automated perfusion software has gained importance for imaging of stroke patients for mechanical thrombectomy (MT). We aim to compare four perfusion software packages: 1) with respect to their association with 3-month functional outcome after successful reperfusion with MT in comparison to visual Cerebral Blood Volume - Alberta Stroke Program Early CT Score (CBV-ASPECTS) and collateral scoring and 2) with respect to their agreement in estimation of core and penumbra volume. Methods This retrospective, multicenter cohort study (2015-2019) analyzed data from 8 centers. We included patients who were functionally independent before and underwent successful MT of the middle cerebral artery. Primary outcome measurements were the relationship of core and penumbra volume calculated by each software, qualitative assessment of collaterals and CBV-APECTS with 3-month functional outcome and disability (modified Rankin scale >2). Quantitative differences between perfusion software measurements were also assessed. Results A total of 215 patients (57% women, median age 77 years) from 8 centers fulfilled the inclusion criteria. Multivariable analyses showed a significant association of RAPID core (common odds ratio, cOR 1.02; p = 0.015), CBV-ASPECTS (cOR 0.78; p = 0.007) and collaterals (cOR 0.78; p = 0.001) with 3-month functional outcome (shift analysis), while RAPID core (OR 1.02; p = 0.018), CBV-ASPECTS (OR 0.77; p = 0.024), collaterals (OR 0.78; p = 0.007) and OLEA core (OR 1.02; p = 0.029) were significantly associated with 3-month functional disability. Mean differences on core estimates between VEOcore and RAPID were 13.4 ml, between syngo.via and RAPID 30.0 ml and between OLEA and RAPID -3.2 ml. Conclusion Collateral scoring, CBV-ASPECTS and RAPID were independently associated with functional outcome at 90 days. Core and Penumbra estimates using automated software packages varied significantly and should therefore be used with caution.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Psychogios, Marios-NikosUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sporns, Peter B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ospel, JohannaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Katsanos, Aristeidis H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kabiri, RezaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Flottmann, Fabian A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Menon, Bijoy K.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Horn, MackenzieUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Liebeskind, David S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Honda, TristanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ribo, MarcUNSPECIFIEDorcid.org/0000-0001-9242-043XUNSPECIFIED
Ruiz, Manuel RequenaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kabbasch, ChristophUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lichtenstein, ThorstenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Maurer, Christoph J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Berlis, AnsgarUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hellstern, VictoriaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Henkes, HansUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Moehlenbruch, Markus A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Seker, FatihUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ernst, Marielle S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Liman, JanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tsivgoulis, GeorgiosUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Brehm, AlexUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-311020
DOI: 10.1007/s00062-020-00974-3
Journal or Publication Title: Clin. Neuroradiol.
Publisher: SPRINGER HEIDELBERG
Place of Publication: HEIDELBERG
ISSN: 1869-1447
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
ACUTE ISCHEMIC-STROKE; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; LARGE VESSEL OCCLUSION; FINAL INFARCT VOLUME; CT PERFUSION; MANAGEMENT; THROMBECTOMY; THRESHOLDS; PENUMBRAMultiple languages
Clinical Neurology; Radiology, Nuclear Medicine & Medical ImagingMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/31102

Downloads

Downloads per month over past year

Altmetric

Export

Actions (login required)

View Item View Item