Universität zu Köln

de Vos, Chloe, Leopold, Karolina, Blanke, Elisabeth S., Siebert, Stefan, Baumgardt, Johanna, Burkhardt, Eva and Bechdolf, Andreas (2020). The relationship between cannabis use and cognition in people diagnosed with first-episode psychosis. Psychiatry Res., 293. CLARE: ELSEVIER IRELAND LTD. ISSN 0165-1781

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Abstract

Cannabis use is highly prevalent among young people diagnosed with first-episode psychosis (FEP), however, its impact on cognition is still unclear. The aim of the present study was to examine the association of cannabis use with cognition in people diagnosed with FEP. We extended previous research findings by operationalising the comorbid cannabis use, considering recency of cannabis use and use of other illicit substances and including people with a broad spectrum of psychotic diagnoses. A total of 89 people diagnosed with FEP were interviewed about their history of substance use and completed a cognitive test battery assessing verbal memory, verbal fluency and attention. Sixty-one participants were lifetime cannabis users (CU; >= three times per week for >= four weeks; 68.5%) and 28 were cannabis non-users (CNU; 31.5%). CU were significantly more likely to be male and exhibited significantly more positive symptoms than CNU. In contrast, CNU displayed significantly more negative symptoms than CU. There were no differences between CU and CNU on neurocognitive tasks of verbal memory, verbal fluency and attention. In conclusion, there was no indication that cannabis use was associated with cognitive impairments in people diagnosed with FEP.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code de Vos, Chloe UNSPECIFIED UNSPECIFIED UNSPECIFIED Leopold, Karolina UNSPECIFIED UNSPECIFIED UNSPECIFIED Blanke, Elisabeth S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Siebert, Stefan UNSPECIFIED UNSPECIFIED UNSPECIFIED Baumgardt, Johanna UNSPECIFIED UNSPECIFIED UNSPECIFIED Burkhardt, Eva UNSPECIFIED UNSPECIFIED UNSPECIFIED Bechdolf, Andreas UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-312638
DOI:	10.1016/j.psychres.2020.113424
Journal or Publication Title:	Psychiatry Res.
Volume:	293
Date:	2020
Publisher:	ELSEVIER IRELAND LTD
Place of Publication:	CLARE
ISSN:	0165-1781
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CLINICAL CHARACTERISTICS; EARLY INTERVENTION; ONSET; SCHIZOPHRENIA; DISORDERS; THERAPY; ABUSE; RISK; AGE Multiple languages Psychiatry Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/31263