Universität zu Köln

Mirzaei, Masoud ORCID: 0000-0002-7256-4601, Zarch, Malihe Babaei, Darroudi, Mahdieh ORCID: 0000-0002-9152-2642, Sayyadi, Khalilollah, Keshavarz, Seyed Tahmoures, Sayyadi, Jalil, Fallah, Azadeh and Maleki, Hajar (2020). Silica Mesoporous Structures: Effective Nanocarriers in Drug Delivery and Nanocatalysts. Appl. Sci.-Basel, 10 (21). BASEL: MDPI. ISSN 2076-3417

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Abstract

The application of silica mesoporous structures in drug delivery and the removal of pollutants and organic compounds through catalytic reactions is increasing due to their unique characteristics, including high loading capacities, tunable pores, large surface areas, sustainability, and so on. This review focuses on very well-studied class of different construction mesoporous silica nano(particles), such as MCM-41, SBA-15, and SBA-16. We discuss the essential parameters involved in the synthesis of these materials with providing a diverse set of examples. In addition, the recent advances in silica mesoporous structures for drug delivery and catalytic applications are presented to fill the existing gap in the literature with providing some promising examples on this topic for the scientists in both industry and academia active in the field. Regarding the catalytic applications, mesoporous silica particles have shown some promises to remove the organic pollutants and to synthesize final products with high yields due to the ease with which their surfaces can be modified with various ligands to create appropriate interactions with target molecules. In the drug delivery process, as nanocarriers, they have also shown very good performance thanks to the easy surface functionalization but also adjustability of their porosities to providing in-vivo and in-vitro cargo delivery at the target site with appropriate rate.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Mirzaei, Masoud UNSPECIFIED orcid.org/0000-0002-7256-4601 UNSPECIFIED Zarch, Malihe Babaei UNSPECIFIED UNSPECIFIED UNSPECIFIED Darroudi, Mahdieh UNSPECIFIED orcid.org/0000-0002-9152-2642 UNSPECIFIED Sayyadi, Khalilollah UNSPECIFIED UNSPECIFIED UNSPECIFIED Keshavarz, Seyed Tahmoures UNSPECIFIED UNSPECIFIED UNSPECIFIED Sayyadi, Jalil UNSPECIFIED UNSPECIFIED UNSPECIFIED Fallah, Azadeh UNSPECIFIED UNSPECIFIED UNSPECIFIED Maleki, Hajar UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-312843
DOI:	10.3390/app10217533
Journal or Publication Title:	Appl. Sci.-Basel
Volume:	10
Number:	21
Date:	2020
Publisher:	MDPI
Place of Publication:	BASEL
ISSN:	2076-3417
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language RESPONSIVE CONTROLLED-RELEASE; LOW-REFRACTIVE-INDEX; PORE-SIZE; OXIDE NANOPARTICLES; SURFACTANT SOLUTIONS; THERMAL-STABILITY; ACTIVATED CARBON; POROUS MATERIALS; NANOPOROUS SIO2; ARYL HALIDES Multiple languages Chemistry, Multidisciplinary; Engineering, Multidisciplinary; Materials Science, Multidisciplinary; Physics, Applied Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/31284