Felinska, Eleni ORCID: 0000-0002-3838-1625, Billeter, Adrian ORCID: 0000-0001-8724-4793, Nickel, Felix, Contin, Pietro, Berlth, Felix, Chand, Bipan, Grimminger, Peter ORCID: 0000-0002-1859-9213, Mikami, Dean, Schoppmann, Sebastian F. ORCID: 0000-0002-1725-7086 and Mueller-Stich, Beat . Do we understand the pathophysiology of GERD after sleeve gastrectomy? Ann. N.Y. Acad. Sci.. HOBOKEN: WILEY. ISSN 1749-6632

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Abstract

Gastroesophageal reflux disease (GERD), a prevalent problem among obese individuals, is strongly associated with obesity and weight loss. Hence, bariatric surgery effectively improves GERD for many patients. Depending on the type of bariatric procedure, however, surgery can also worsen or even cause a new onset of GERD. As a consequence, GERD remains a relevant problem for many bariatric patients, and especially those who have undergone sleeve gastrectomy (SG). Affected patients report not only a decrease in physical functioning but also suffer from mental and emotional problems, resulting in poorer social functioning. The pathomechanism of GERD after SG is most likely multifactorial and triggered by the interaction of anatomical, physiological, and physical factors. Contributing factors include the shape of the sleeve, the extent of injury to the lower esophageal sphincter, and the presence of hiatal hernia. In order to successfully treat post-sleeve gastrectomy GERD, the cause of the problem must first be identified. Therapeutic approaches include lifestyle changes, medication, interventional treatment, and/or revisional surgery.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Felinska, EleniUNSPECIFIEDorcid.org/0000-0002-3838-1625UNSPECIFIED
Billeter, AdrianUNSPECIFIEDorcid.org/0000-0001-8724-4793UNSPECIFIED
Nickel, FelixUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Contin, PietroUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Berlth, FelixUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Chand, BipanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Grimminger, PeterUNSPECIFIEDorcid.org/0000-0002-1859-9213UNSPECIFIED
Mikami, DeanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schoppmann, Sebastian F.UNSPECIFIEDorcid.org/0000-0002-1725-7086UNSPECIFIED
Mueller-Stich, BeatUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-319653
DOI: 10.1111/nyas.14467
Journal or Publication Title: Ann. N.Y. Acad. Sci.
Publisher: WILEY
Place of Publication: HOBOKEN
ISSN: 1749-6632
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
Y-GASTRIC BYPASS; GASTROESOPHAGEAL-REFLUX DISEASE; LOWER ESOPHAGEAL SPHINCTER; QUALITY-OF-LIFE; PROTON-PUMP INHIBITORS; INTENSIVE MEDICAL THERAPY; BARIATRIC SURGERY; WEIGHT-LOSS; BARRETTS-ESOPHAGUS; BALLOON DILATIONMultiple languages
Multidisciplinary SciencesMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/31965

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