Gaebel, Wolfgang, Zaeske, Harald, Hesse, Klaus, Klingberg, Stefan ORCID: 0000-0001-8081-7181, Ohmann, Christian, Grebe, Juergen, Kolbe, Henrike, Icks, Andrea, Schneider, Frank, Backes, Volker, Wolff-Menzler, Claus, Guse, Birgit, Gallinat, Juergen, Bock, Thomas, Jockers-Scheruebl, Maria-Christiane, Krueger, Timo, Jessen, Frank, Bechdolf, Andreas, Kircher, Tilo, Konrad, Carsten, Falkai, Peter ORCID: 0000-0003-2873-8667, Schaub, Annette, Rudolph, Matthias, Koellner, Volker, Schmid-Ott, Gerhard, Linden, Michael, Lieberei, Barbara, Stuhlinger, Monika, Sommerfeld, Sebastian, Schumacher, Albrecht, Krenge, Sabine, Gereke, Stephanie, Moenter, Norbert, Navarro-Urena, Alicia, Frosch, Guenter, Kuhlbusch, Franz-Josef, Cleveland, Helen and Riesbeck, Mathias (2020). Promoting stigma coping and empowerment in patients with schizophrenia and depression: results of a cluster-RCT. Eur. Arch. Psych. Clin. Neurosci., 270 (5). S. 501 - 512. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1433-8491

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Abstract

There is a need for interventions supporting patients with mental health conditions in coping with stigma and discrimination. A psycho-educational group therapy module to promote stigma coping and empowerment (STEM) was developed and tested for efficacy in patients with schizophrenia or depression. 30 clinical centers participated in a cluster-randomized clinical trial, representing a broad spectrum of mental health care settings: in-patient (acute treatment, rehabilitation), out-patient, and day-hospitals. As randomized, patients in the intervention group clusters/centers received an illness-specific eight sessions standard psychoeducational group therapy plus three specific sessions on stigma coping and empowerment ('STEM'). In the control group clusters the same standard psychoeducational group therapy was extended to 11 sessions followed by one booster session in both conditions. In total,N = 462 patients were included in the analysis (N = 117 with schizophrenia spectrum disorders, ICD-10 F2x;N = 345 with depression, ICD-10 F31.3-F31.5, F32-F34, and F43.2). Clinical and stigma-related measures were assessed before and directly after treatment, as well as after 6 weeks, 6 months, and 12 months (M12). Primary outcome was improvement in quality of life (QoL) assessed with the WHO-QOL-BREF between pre-assessment and M12 analyzed by mixed models and adjusted for pre-treatment differences. Overall, QoL and secondary outcome measures (symptoms, functioning, compliance, internalized stigma, self-esteem, empowerment) improved significantly, but there was no significant difference between intervention and control group. The short STEM module has proven its practicability as an add-on in different settings in routine mental health care. The overall increase in empowerment in both, schizophrenia and depression, indicates patients' treatment benefit. However, factors contributing to improvement need to be explored. The study has been registered in the following trial registers. ClinicalTrials.gov:Registration number: NCT01655368. DRKS:Registration number: DRKS00004217.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Gaebel, WolfgangUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Zaeske, HaraldUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hesse, KlausUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Klingberg, StefanUNSPECIFIEDorcid.org/0000-0001-8081-7181UNSPECIFIED
Ohmann, ChristianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Grebe, JuergenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kolbe, HenrikeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Icks, AndreaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schneider, FrankUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Backes, VolkerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wolff-Menzler, ClausUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Guse, BirgitUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gallinat, JuergenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bock, ThomasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jockers-Scheruebl, Maria-ChristianeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Krueger, TimoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jessen, FrankUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bechdolf, AndreasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kircher, TiloUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Konrad, CarstenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Falkai, PeterUNSPECIFIEDorcid.org/0000-0003-2873-8667UNSPECIFIED
Schaub, AnnetteUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rudolph, MatthiasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Koellner, VolkerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schmid-Ott, GerhardUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Linden, MichaelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lieberei, BarbaraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stuhlinger, MonikaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sommerfeld, SebastianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schumacher, AlbrechtUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Krenge, SabineUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gereke, StephanieUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Moenter, NorbertUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Navarro-Urena, AliciaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Frosch, GuenterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kuhlbusch, Franz-JosefUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cleveland, HelenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Riesbeck, MathiasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-325377
DOI: 10.1007/s00406-019-01064-3
Journal or Publication Title: Eur. Arch. Psych. Clin. Neurosci.
Volume: 270
Number: 5
Page Range: S. 501 - 512
Date: 2020
Publisher: SPRINGER HEIDELBERG
Place of Publication: HEIDELBERG
ISSN: 1433-8491
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
HEALTH-RELATED STIGMA; SELF-STIGMA; INTERNALIZED STIGMA; MENTAL-ILLNESS; PSYCHOMETRIC PROPERTIES; DISCRIMINATION; INTERVENTIONS; DISORDERS; IMPACT; METAANALYSISMultiple languages
Clinical Neurology; PsychiatryMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/32537

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