Universität zu Köln

Pahmeyer, Caroline, Schablack, Anika, Ratiu, Dominik, Thangarajah, Fabinshy, Ludwig, Sebastian, Gruettner, Berthold, Mallmann, Peter, Malter, Wolfram, Warm, Mathias and Eichler, Christian (2020). Occurrence of Residual Cancer Within Re-excisions After Subcutaneous Mastectomy of Invasive Breast Cancer and Ductal Carcinoma In Situ - A Retrospective Analysis. In Vivo, 34 (4). S. 2015 - 2020. ATHENS: INT INST ANTICANCER RESEARCH. ISSN 1791-7549

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Abstract

Background/Aim: Surgical margin status remains an important determinant for recurrence of invasive breast cancer and ductal carcinoma in situ. We compared the number of positive margins in initial histology with rates of residual tumor in re-excision specimens. Furthermore, we analysed cost-effectiveness of re-excisions. Patients and Methods: 101 patients treated with secondary surgery were included. The first group underwent breast conserving surgery and secondary mastectomy. The second group was primarily treated with subcutaneous mastectomy followed by secondary surgery. Results: Within the first group, 22.7% did not show residual tumor in the re-excision specimen. Of the second group, 54.3% had no residual tumor. Consequentially 45.7% needed a re-excision to achieve R0 status. Cost-effectiveness was determined as secondary endpoint. If a patient needs a secondary mastectomy the hospital gains 602,65(sic) in comparison to a primary breast conserving operation. Conclusion: In every second patient who had first received a subcutaneous mastectomy, no tumor could be detected in the secondary operation despite a previous R1 status.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Pahmeyer, Caroline UNSPECIFIED UNSPECIFIED UNSPECIFIED Schablack, Anika UNSPECIFIED UNSPECIFIED UNSPECIFIED Ratiu, Dominik UNSPECIFIED UNSPECIFIED UNSPECIFIED Thangarajah, Fabinshy UNSPECIFIED UNSPECIFIED UNSPECIFIED Ludwig, Sebastian UNSPECIFIED UNSPECIFIED UNSPECIFIED Gruettner, Berthold UNSPECIFIED UNSPECIFIED UNSPECIFIED Mallmann, Peter UNSPECIFIED UNSPECIFIED UNSPECIFIED Malter, Wolfram UNSPECIFIED UNSPECIFIED UNSPECIFIED Warm, Mathias UNSPECIFIED UNSPECIFIED UNSPECIFIED Eichler, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-327324
DOI:	10.21873/invivo.12000
Journal or Publication Title:	In Vivo
Volume:	34
Number:	4
Page Range:	S. 2015 - 2020
Date:	2020
Publisher:	INT INST ANTICANCER RESEARCH
Place of Publication:	ATHENS
ISSN:	1791-7549
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language SURGICAL MARGINS; RECURRENCE; SURGERY; PREDICTORS; DISEASE Multiple languages Medicine, Research & Experimental Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/32732