Universität zu Köln

Kotsis, Vasiliosa, Jordan, Jens, Stabouli, Stella, Antza, Christina, Micic, Dragane, Jelakovic, Bojanf, Schlaich, Markus P., Nilsson, Peter M., Kreutz, Reinhold, Mancia, Giuseppe, Tsioufis, Kostas and Grassi, Guido (2020). Cardiovascular, renal and liver protection with novel antidiabetic agents beyond blood glucose lowering in type 2 diabetes: consensus article from the European Society of Hypertension Working Group on Obesity, Diabetes and the High-risk Patient. J. Hypertens., 38 (3). S. 377 - 387. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1473-5598

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Abstract

The prevalence of type 2 diabetes (T2D) has increased over the past few decades. T2D has a strong genetic propensity that becomes overt when a patient is exposed to a typical Western lifestyle, gain weight and becomes obese, whereas weight loss protects from the development of T2D. Except of lifestyle modifications, the choice of the appropriate treatment is essential in the management of patients with T2D and appears critical for the obese population with T2D. The new pharmacological approach for the treatment of T2D, sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide 1 receptor agonists, seems to be effective not only in the management of T2D but also for weight loss, reduction of blood pressure and improvement of nonalcoholic fatty liver disease. Sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide 1 analogues reduced cardiovascular risk, prevented cardiovascular disease and mortality, thereby playing an important role in the treatment of obese patients with hypertension and T2D.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Kotsis, Vasiliosa UNSPECIFIED UNSPECIFIED UNSPECIFIED Jordan, Jens UNSPECIFIED UNSPECIFIED UNSPECIFIED Stabouli, Stella UNSPECIFIED UNSPECIFIED UNSPECIFIED Antza, Christina UNSPECIFIED UNSPECIFIED UNSPECIFIED Micic, Dragane UNSPECIFIED UNSPECIFIED UNSPECIFIED Jelakovic, Bojanf UNSPECIFIED UNSPECIFIED UNSPECIFIED Schlaich, Markus P. UNSPECIFIED UNSPECIFIED UNSPECIFIED Nilsson, Peter M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Kreutz, Reinhold UNSPECIFIED UNSPECIFIED UNSPECIFIED Mancia, Giuseppe UNSPECIFIED UNSPECIFIED UNSPECIFIED Tsioufis, Kostas UNSPECIFIED UNSPECIFIED UNSPECIFIED Grassi, Guido UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-342429
DOI:	10.1097/HJH.0000000000002279
Journal or Publication Title:	J. Hypertens.
Volume:	38
Number:	3
Page Range:	S. 377 - 387
Date:	2020
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Place of Publication:	PHILADELPHIA
ISSN:	1473-5598
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language GLUCAGON-LIKE PEPTIDE-1; COTRANSPORTER 2 INHIBITORS; GLP-1 RECEPTOR AGONISTS; LIRAGLUTIDE 3.0 MG; INSULIN-RESISTANCE; DOUBLE-BLIND; WEIGHT-LOSS; HEART-RATE; SODIUM; DISEASE Multiple languages Peripheral Vascular Disease Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/34242