D'Ascenzo, Fabrizio ORCID: 0000-0002-6646-9317, Gili, Sebastiano, Bertaina, Maurizio ORCID: 0000-0001-5727-4107, Iannaccone, Mario ORCID: 0000-0003-0571-3918, Cammann, Victoria L., Di Vece, Davide, Kato, Ken, Saglietto, Andrea ORCID: 0000-0001-9475-1507, Szawan, Konrad A., Frangieh, Antonio H., Boffini, Beatrice, Annaratone, Margherita, Sarcon, Annahita, Levinson, Rena A., Franke, Jennifer, Napp, L. Christian ORCID: 0000-0001-9945-0842, Jaguszewski, Milosz, Noutsias, Michel, Muenzel, Thomas ORCID: 0000-0001-5503-4150, Knorr, Maike, Heiner, Susanne, Katus, Hugo A., Burgdorf, Christof, Schunkert, Heribert, Thiele, Holger ORCID: 0000-0002-0169-998X, Bauersachs, Johann, Tschoepe, Carsten, Pieske, Burkert M., Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Hasenfuss, Gerd, Karakas, Mahir, Koenig, Wolfgang, Rottbauer, Wolfgang, Said, Samir M., Braun-Dullaeus, Ruediger C., Banning, Adrian ORCID: 0000-0002-2842-7861, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Opolski, Grzegorz, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Crea, Filippo, Dichtl, Wolfgang, Franz, Wolfgang M., Empen, Klaus, Felix, Stephan B., Delmas, Clement, Lairez, Olivier, El-Battrawy, Ibrahim, Akin, Ibrahim, Borggrefe, Martin, Horowitz, John D., Kozel, Martin, Tousek, Petr, Widimsky, Petr, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, Biondi-Zoccai, Giuseppe ORCID: 0000-0001-6103-8510, Winchester, David E., Ukena, Christian, Neuhaus, Michael, Bax, Jeroen J., Prasad, Abhiram, Di Mario, Carlo, Boehm, Michael, Gasparini, Mauro, Ruschitzka, Frank, Bossone, Eduardo, Citro, Rodolfo, Rinaldi, Mauro, De Ferrari, Gaetano Maria, Luscher, Thomas, Ghadri, Jelena R. and Templin, Christian (2020). Impact of aspirin on takotsubo syndrome: a propensity score-based analysis of the InterTAK Registry. Eur. J. Heart Fail., 22 (2). S. 330 - 338. HOBOKEN: WILEY. ISSN 1879-0844

Full text not available from this repository.

Abstract

AimsThe aim of the present study was to investigate the impact of aspirin on prognosis in takotsubo syndrome (TTS). Methods and resultsPatients from the International Takotsubo (InterTAK) Registry were categorized into two groups based on aspirin prescription at discharge. A comparison of clinical outcomes between groups was performed using an adjusted analysis with propensity score (PS) stratification; results from the unadjusted analysis were also reported to note the effect of the PS adjustment. Major adverse cardiac and cerebrovascular events (MACCE: a composite of death, myocardial infarction, TTS recurrence, stroke or transient ischaemic attack) were assessed at 30-day and 5-year follow-up. A total of 1533 TTS patients with known status regarding aspirin prescription at discharge were included. According to the adjusted analysis based on PS stratification, aspirin was not associated with a lower hazard of MACCE at 30-day [hazard ratio (HR) 1.24, 95% confidence interval (CI) 0.50-3.04, P = 0.64] or 5-year follow-up (HR 1.11, 95% CI 0.78-1.58, P = 0.58). These results were confirmed by sensitivity analyses performed with alternative PS-based methods, i.e. covariate adjustment and inverse probability of treatment weighting. ConclusionIn the present study, no association was found between aspirin use in TTS patients and a reduced risk of MACCE at 30-day and 5-year follow-up. These findings should be confirmed in adequately powered randomized controlled trials. Identifier: NCT01947621.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
D'Ascenzo, FabrizioUNSPECIFIEDorcid.org/0000-0002-6646-9317UNSPECIFIED
Gili, SebastianoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bertaina, MaurizioUNSPECIFIEDorcid.org/0000-0001-5727-4107UNSPECIFIED
Iannaccone, MarioUNSPECIFIEDorcid.org/0000-0003-0571-3918UNSPECIFIED
Cammann, Victoria L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Di Vece, DavideUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kato, KenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Saglietto, AndreaUNSPECIFIEDorcid.org/0000-0001-9475-1507UNSPECIFIED
Szawan, Konrad A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Frangieh, Antonio H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Boffini, BeatriceUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Annaratone, MargheritaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sarcon, AnnahitaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Levinson, Rena A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Franke, JenniferUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Napp, L. ChristianUNSPECIFIEDorcid.org/0000-0001-9945-0842UNSPECIFIED
Jaguszewski, MiloszUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Noutsias, MichelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Muenzel, ThomasUNSPECIFIEDorcid.org/0000-0001-5503-4150UNSPECIFIED
Knorr, MaikeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Heiner, SusanneUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Katus, Hugo A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Burgdorf, ChristofUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schunkert, HeribertUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Thiele, HolgerUNSPECIFIEDorcid.org/0000-0002-0169-998XUNSPECIFIED
Bauersachs, JohannUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tschoepe, CarstenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pieske, Burkert M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rajan, LawrenceUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Michels, GuidoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pfister, RomanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cuneo, AlessandroUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jacobshagen, ClaudiusUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hasenfuss, GerdUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Karakas, MahirUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Koenig, WolfgangUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rottbauer, WolfgangUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Said, Samir M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Braun-Dullaeus, Ruediger C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Banning, AdrianUNSPECIFIEDorcid.org/0000-0002-2842-7861UNSPECIFIED
Cuculi, FlorimUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kobza, RichardUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Fischer, Thomas A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Vasankari, TuijaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Airaksinen, K. E. JuhaniUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Opolski, GrzegorzUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dworakowski, RafalUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
MacCarthy, PhilipUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kaiser, ChristophUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Osswald, StefanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Galiuto, LeonardaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Crea, FilippoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dichtl, WolfgangUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Franz, Wolfgang M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Empen, KlausUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Felix, Stephan B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Delmas, ClementUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lairez, OlivierUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
El-Battrawy, IbrahimUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Akin, IbrahimUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Borggrefe, MartinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Horowitz, John D.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kozel, MartinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tousek, PetrUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Widimsky, PetrUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gilyarova, EkaterinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Shilova, AlexandraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gilyarov, MikhailUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Biondi-Zoccai, GiuseppeUNSPECIFIEDorcid.org/0000-0001-6103-8510UNSPECIFIED
Winchester, David E.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ukena, ChristianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Neuhaus, MichaelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bax, Jeroen J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Prasad, AbhiramUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Di Mario, CarloUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Boehm, MichaelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gasparini, MauroUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ruschitzka, FrankUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bossone, EduardoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Citro, RodolfoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rinaldi, MauroUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
De Ferrari, Gaetano MariaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Luscher, ThomasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ghadri, Jelena R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Templin, ChristianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-346309
DOI: 10.1002/ejhf.1698
Journal or Publication Title: Eur. J. Heart Fail.
Volume: 22
Number: 2
Page Range: S. 330 - 338
Date: 2020
Publisher: WILEY
Place of Publication: HOBOKEN
ISSN: 1879-0844
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
APICAL BALLOONING SYNDROME; CLINICAL PROFILE; TAKO-TSUBO; CARDIOMYOPATHY; RECURRENCE; PROGNOSIS; OUTCOMES; MORTALITY; FEATURES; THERAPYMultiple languages
Cardiac & Cardiovascular SystemsMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/34630

Downloads

Downloads per month over past year

Altmetric

Export

Actions (login required)

View Item View Item