Goertz, Lukas, Smyk, Michael Artur, Siebert, Eberhard, Turowski, Bernd, Borggrefe, Jan ORCID: 0000-0003-2908-7560, Mpotsaris, Anastasios ORCID: 0000-0002-1275-8164, Bohner, Georg, Schlamann, Marc, Dorn, Franziska, Liebig, Thomas and Kabbasch, Christoph . Low-Profile Laser-Cut Stents for Endovascular Treatment of Intracranial Aneurysms Incidence, Clinical Presentation and Risk Factors of Thromboembolic Events. Clin. Neuroradiol.. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1869-1447

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Abstract

Purpose Low-profile intracranial stents are characterized by a miniaturized design that enables deployment via a 0.0165 '' or 0.017 '' internal diameter microcatheter, which is typically intended for coil delivery. This study analyzed the incidence, clinical relevance and risk factors of thromboembolic events (TEE) occurring during low-profile stent-assisted coiling of intracranial aneurysms. Methods This was a retrospective, multicenter analysis of consecutive patients who underwent stent-assisted aneurysm coiling (SAC) with the laser-cut Acandis Acclino and Neuroform Atlas stents. The study evaluated the incidence of symptomatic and asymptomatic TEEs and the impact on functional outcome. Risk factors for TEEs were determined by univariate and bivariate logistic regression analyses. Results Among 131 procedures (mean patient age 56.5 +/- 12.8 years, mean aneurysm size: 6.7 +/- 3.9mm) TEEs occurred in 14 cases (10.7%) of which 2 patients (1.5%) developed ischemic stroke, while the remaining TEEs remained asymptomatic. Multivariate analysis revealed Y-stenting as potential risk factor for TEEs (odds ratio: 3.9, 95% confidence interval: 1.0-16.5; p= 0.08). Conclusion The use of SAC with low-profile intracranial stents is associated with a favorable safety profile; however, Y-stenting may carry an increased risk of TEEs, which needs to be considered during treatment planning.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Goertz, LukasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Smyk, Michael ArturUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Siebert, EberhardUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Turowski, BerndUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Borggrefe, JanUNSPECIFIEDorcid.org/0000-0003-2908-7560UNSPECIFIED
Mpotsaris, AnastasiosUNSPECIFIEDorcid.org/0000-0002-1275-8164UNSPECIFIED
Bohner, GeorgUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schlamann, MarcUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dorn, FranziskaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Liebig, ThomasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kabbasch, ChristophUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-348449
DOI: 10.1007/s00062-019-00874-1
Journal or Publication Title: Clin. Neuroradiol.
Publisher: SPRINGER HEIDELBERG
Place of Publication: HEIDELBERG
ISSN: 1869-1447
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
ASSISTED COIL EMBOLIZATION; WIDE-NECKED ANEURYSMS; Y-CONFIGURATION; COMPLICATIONS; EFFICACY; COMPLEX; SAFETY; ENTERPRISE; DEVICEMultiple languages
Clinical Neurology; Radiology, Nuclear Medicine & Medical ImagingMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/34844

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