Universität zu Köln

KaKkassery, Vinodh, Emmert, Steffen, Rades, Dirk, von Bubnoff, Nikolas, Ranjbar, Mahdy, Grisanti, Salvatore, Chronopoulos, Argyrios, Heindl, Ludwig M. and Adamietz, Irenaeus A. (2020). Ophthalmic emergencies in tumor patients. Onkologe, 26 (2). S. 151 - 157. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1433-0415

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Abstract

Background Morphologic alterations of the eye may lead to worsening of vision, but might also be a sign of a life-threatening situation in cancer patients. Objective The aim of this study was to provide a description of acute ocular situations in cancer patients. The attention toward clinical signs and symptoms of acute ophthalmic situations should be heightened in tumor patients. Methods This study is based on a literature search with a structured display and analysis of the results. Results Immune reactions to non-ocular tumor tissue or systemic cancer therapies can lead to vision-reducing ocular inflammation. Clinical manifestations in the eye, e.g., Roth spots on the retina, indicate leukemia and may be life threatening. Ocular metastases, whether from a known primary or a first diagnosis, must be further investigated; due to the common hematogenous metastasis pathways via the carotids, additional central nervous system (CNS) metastases are often found. Seriously ill patients with sepsis often develop endogenous endophthalmitis with bacteria or fungi, with a generally reduced life expectancy. Periorbital skin irritations after irradiation of ocular tumors might worry the patient, but usually heal by themselves. Conclusion An ophthalmologic examination can correctly classify loss of vision and uncover life-threatening situations. Corresponding initiation or interruption of treatment may control the situation. Clarification of ocular symptoms can be of particular value for burdened tumor patients. Therefore, an ophthalmologist with oncologic experience is a valuable member of every interdisciplinary tumor team.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code KaKkassery, Vinodh UNSPECIFIED UNSPECIFIED UNSPECIFIED Emmert, Steffen UNSPECIFIED UNSPECIFIED UNSPECIFIED Rades, Dirk UNSPECIFIED UNSPECIFIED UNSPECIFIED von Bubnoff, Nikolas UNSPECIFIED UNSPECIFIED UNSPECIFIED Ranjbar, Mahdy UNSPECIFIED UNSPECIFIED UNSPECIFIED Grisanti, Salvatore UNSPECIFIED UNSPECIFIED UNSPECIFIED Chronopoulos, Argyrios UNSPECIFIED UNSPECIFIED UNSPECIFIED Heindl, Ludwig M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Adamietz, Irenaeus A. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-348644
DOI:	10.1007/s00761-019-00694-5
Journal or Publication Title:	Onkologe
Volume:	26
Number:	2
Page Range:	S. 151 - 157
Date:	2020
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1433-0415
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language AUTOIMMUNE RETINOPATHY; ROTH SPOTS; IPILIMUMAB; MELANOMA; DIAGNOSTICS; NIVOLUMAB; FEATURES; EYE Multiple languages Oncology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/34864