Universität zu Köln

Schmidt, Matthias C., Uhrhan, Klara, Fischer, Thomas, Schmitz, Stephan, Markiefka, Birgid, Drzezga, Alexander and Stippel, Dirk ORCID: 0000-0002-1107-0907 (2015). Complete Remission of Metastatic Neuroendocrine Paragastric Carcinoma After Neoadjuvant Peptide Receptor Radionuclide Therapy and Surgery. Clin. Nucl. Med., 40 (8). S. 667 - 670. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1536-0229

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Abstract

A 48-year-old man presenting with upper abdominal pain was diagnosed with neuroendocrine tumor after biopsy of a paragastric mass with multiple liver metastases. Ga-68-DOTATATE PET/CT showed intense uptake in the paragastric tumor and in multiple liver metastases not allowing primary surgery. Two cycles with cumulative 14.6 GBq Lu-177-DOTATATE were given resulting in a considerable improvement. Subsequent surgery resulted in a complete remission as demonstrated by Ga-68-DOTATATE PET/CT. Usually, peptide receptor radionuclide (PRRT) therapy is considered a palliative treatment. Few patients demonstrate a very favorable response allowing resection of the primary tumor after downstaging metastatic disease burden.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Schmidt, Matthias C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Uhrhan, Klara UNSPECIFIED UNSPECIFIED UNSPECIFIED Fischer, Thomas UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmitz, Stephan UNSPECIFIED UNSPECIFIED UNSPECIFIED Markiefka, Birgid UNSPECIFIED UNSPECIFIED UNSPECIFIED Drzezga, Alexander UNSPECIFIED UNSPECIFIED UNSPECIFIED Stippel, Dirk UNSPECIFIED orcid.org/0000-0002-1107-0907 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-398015
DOI:	10.1097/RLU.0000000000000805
Journal or Publication Title:	Clin. Nucl. Med.
Volume:	40
Number:	8
Page Range:	S. 667 - 670
Date:	2015
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Place of Publication:	PHILADELPHIA
ISSN:	1536-0229
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language RADIOLABELED SOMATOSTATIN ANALOG; TUMORS Multiple languages Radiology, Nuclear Medicine & Medical Imaging Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/39801