Hoang-Xuan, Khe, Bessell, Eric, Bromberg, Jacoline, Hottinger, Andreas F., Preusser, Matthias ORCID: 0000-0003-3541-2315, Ruda, Roberta, Schlegel, Talli, Soussain, Carole, Abacioglu, Ufuk ORCID: 0000-0002-3950-8616, Cassoux, Nathalie, Deckert, Martina, Dirven, Siemens M. F., Ferreri, Andres J. M., Graus, Francesc ORCID: 0000-0002-8924-8322, Henriksson, Roger, Herdinger, Ulric, Taphoorn, Martin, Soffietti, Riccardo and Weller, Michael ORCID: 0000-0002-1748-174X (2015). Diagnosis and treatment of primary CNS lymphoma in immunocompetent patients: guidelines from the European Association for Neuro-Oncology. Lancet Oncol., 16 (7). S. E322 - 11. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1474-5488

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Abstract

The management of primary CNS lymphoma is one of the most controversial topics in neuro-oncology because of the complexity of the disease and the very few controlled studies available. In 2013, the European Association of Neuro-Oncology created a multidisciplinary task force to establish evidence-based guidelines for immunocompetent adults with primary CNS lymphoma. In this Review, we present these guidelines, which provide consensus considerations and recommendations for diagnosis, assessment, staging, and treatment of primary CNS lymphoma. Specifically, we address aspects of care related to surgery, systemic and intrathecal chemotherapy, intensive chemotherapy with autologous stem-cell transplantation, radiotherapy, intraocular manifestations, and management of elderly patients. The guidelines should aid clinicians in their daily practice and decision making, and serve as a basis for future investigations in neuro-oncology.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Hoang-Xuan, KheUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bessell, EricUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bromberg, JacolineUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hottinger, Andreas F.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Preusser, MatthiasUNSPECIFIEDorcid.org/0000-0003-3541-2315UNSPECIFIED
Ruda, RobertaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schlegel, TalliUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Soussain, CaroleUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Abacioglu, UfukUNSPECIFIEDorcid.org/0000-0002-3950-8616UNSPECIFIED
Cassoux, NathalieUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Deckert, MartinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dirven, Siemens M. F.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ferreri, Andres J. M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Graus, FrancescUNSPECIFIEDorcid.org/0000-0002-8924-8322UNSPECIFIED
Henriksson, RogerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Herdinger, UlricUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Taphoorn, MartinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Soffietti, RiccardoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Weller, MichaelUNSPECIFIEDorcid.org/0000-0002-1748-174XUNSPECIFIED
URN: urn:nbn:de:hbz:38-400485
DOI: 10.1016/S1470-2045(15)00076-5
Journal or Publication Title: Lancet Oncol.
Volume: 16
Number: 7
Page Range: S. E322 - 11
Date: 2015
Publisher: ELSEVIER SCIENCE INC
Place of Publication: NEW YORK
ISSN: 1474-5488
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
NERVOUS-SYSTEM LYMPHOMA; HIGH-DOSE METHOTREXATE; WHOLE-BRAIN RADIOTHERAPY; STEM-CELL TRANSPLANTATION; RECURRENT PRIMARY CNS; TERM-FOLLOW-UP; NON-HODGKINS-LYMPHOMA; MULTICENTER PHASE-II; ELDERLY-PATIENTS; INTENSIVE CHEMOTHERAPYMultiple languages
OncologyMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/40048

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