Kuchenbaecker, Karoline B., Ramus, Susan J., Tyrer, Jonathan, Lee, Andrew, Shen, Howard C., Beesley, Jonathan ORCID: 0000-0003-1942-325X, Lawrenson, Kate, McGuffog, Lesley, Healey, Sue, Lee, Janet M., Spindler, Tassja J., Lin, Yvonne G., Pejovic, Tanja, Bean, Yukie, Li, Qiyuan, Coetzee, Simon ORCID: 0000-0003-4267-5930, Hazelett, Dennis ORCID: 0000-0003-0749-9935, Miron, Alexander, Southey, Melissa ORCID: 0000-0002-6313-9005, Terry, Mary Beth, Goldgar, David E., Buys, Saundra S., Janavicius, Ramunas, Dorfling, Cecilia M., van Rensburg, Elizabeth J., Neuhausen, Susan L., Ding, Yuan Chun, Hansen, Thomas V. O., Jonson, Lars, Gerdes, Anne-Marie ORCID: 0000-0002-0328-3320, Ejlertsen, Bent, Barrowdale, Daniel ORCID: 0000-0003-1661-3939, Dennis, Joe, Benitez, Javier, Osorio, Ana ORCID: 0000-0001-8124-3984, Garcia, Maria Jose, Komenaka, Ian, Weitzel, Jeffrey N., Ganschow, Pamela, Peterlongo, Paolo ORCID: 0000-0001-6951-6855, Bernard, Loris, Viel, Alessandra ORCID: 0000-0003-2804-0840, Bonanni, Bernardo, Peissel, Bernard ORCID: 0000-0001-9233-3571, Manoukian, Siranoush, Radice, Paolo ORCID: 0000-0001-6298-4111, Papi, Laura ORCID: 0000-0003-4552-9517, Ottini, Laura, Fostira, Florentia, Konstantopoulou, Irene ORCID: 0000-0002-0470-0309, Garber, Judy, Frost, Debra, Perkins, Jo, Platte, Radka, Ellis, Steve, Godwin, Andrew K., Schmutzler, Rita Katharina, Meindl, Alfons, Engel, Christoph ORCID: 0000-0002-7247-282X, Sutter, Christian, Sinilnikova, Olga M., Damiola, Francesca ORCID: 0000-0002-0238-1252, Mazoyer, Sylvie ORCID: 0000-0002-2135-0160, Stoppa-Lyonnet, Dominique, Claes, Kathleen ORCID: 0000-0003-0841-7372, De Leeneer, Kim, Kirk, Judy, Rodriguez, Gustavo C., Piedmonte, Marion, O'Malley, David M., de la Hoya, Miguel ORCID: 0000-0002-8113-1410, Caldes, Trinidad, Aittomaeki, Kristiina, Nevanlinna, Heli, Collee, J. Margriet, Rookus, Matti A., Oosterwijk, Jan C., Tihomirova, Laima, Tung, Nadine, Hamann, Ute, Isaccs, Claudine, Tischkowitz, Marc ORCID: 0000-0002-7880-0628, Imyanitov, Evgeny N., Caligo, Maria A., Campbell, Ian G., Hogervorst, Frans B. L., Olah, Edith, Diez, Orland, Blanco, Ignacio ORCID: 0000-0002-7414-7481, Brunet, Joan ORCID: 0000-0003-1945-3512, Lazaroso, Conxi, Angel Pujana, Miguel, Jakubowska, Anna ORCID: 0000-0002-5650-0501, Gronwald, Jacek ORCID: 0000-0002-3643-2871, Lubinski, Jan ORCID: 0000-0003-2931-3003, Sukiennicki, Grzegorz, Barkardottir, Rosa B., Plante, Marie, Simard, Jacques, Soucy, Penny, Montagna, Marco, Tognazzo, Silvia ORCID: 0000-0002-6260-1261, Teixeira, Manuel R., Pankratz, Vernon S., Wang, Xianshu, Lindor, Noralane, Szabo, Csilla I., Kauff, Noah ORCID: 0000-0001-7242-6156, Vijai, Joseph, Aghajanian, Carol A., Pfeiler, Georg, Berger, Andreas, Singer, Christian F., Tea, Muy-Kheng, Phelan, Catherine M., Greene, Mark H., Mai, Phuong L., Rennert, Gad, Mulligan, Anna Marie ORCID: 0000-0002-7239-5297, Tchatchou, Sandrine, Andrulis, Irene L., Glendon, Gord, Toland, Amanda Ewart, Jensen, Uffe Birk ORCID: 0000-0002-6205-6355, Kruse, Torben A., Thomassen, Mads, Bojesen, Anders ORCID: 0000-0003-4289-8595, Zidan, Jamal, Friedman, Eitan, Laitman, Yael, Soller, Maria, Liljegren, Annelie, Arver, Brita, Einbeigi, Zakaria, Stenmark-Askmalm, Marie, Olopade, Olufunmilayo I., Nussbaum, Robert L., Rebbeck, Timothy R., Nathanson, Katherine L., Domchek, Susan M., Lu, Karen H., Karlan, Beth Y., Walsh, Christine, Lester, Jenny, Hein, Alexander ORCID: 0000-0003-2601-3398, Ekici, Arif B., Beckmann, Matthias W., Fasching, Peter A., Lambrechts, Diether ORCID: 0000-0002-3429-302X, Van Nieuwenhuysen, Els, Vergote, Ignace, Lambrechts, Sandrina, Dicks, Ed, Doherty, Jennifer A., Wicklund, Kristine G., Rossing, Mary Anne, Rudolph, Anja, Chang-Claude, Jenny, Wang-Gohrke, Shan, Eilber, Ursula, Moysich, Kirsten B., Odunsi, Kunle, Sucheston, Lara, Lele, Shashi, Wilkens, Lynne R., Goodman, Marc T., Thompson, Pamela J., Shvetsov, Yurii B., Runnebaum, Ingo B., Duerst, Matthias, Hillemanns, Peter, Doerk, Thilo, Antonenkova, Natalia, Bogdanova, Natalia, Leminen, Arto, Pelttari, Liisa M., Butzow, Ralf, Modugno, Francesmary, Kelley, Joseph L., Edwards, Robert P., Ness, Roberta B., du Bois, Andreas, Heitz, Florian ORCID: 0000-0002-2412-0352, Schwaab, Ira, Harter, Philipp, Matsuo, Keitaro ORCID: 0000-0003-1761-6314, Hosono, Satoyo, Orsulic, Sandra, Jensen, Allan ORCID: 0000-0001-8124-4880, Kjaer, Susanne Kruger, Hogdall, Estrid ORCID: 0000-0003-4689-5658, Hasmad, Hanis Nazihah, Azmi, Mat Adenan Noor, Teo, Soo-Hwang, Woo, Yin-Ling, Fridley, Brooke L., Goode, Ellen L., Cunningham, Julie M., Vierkant, Robert A., Bruinsma, Fiona, Giles, Graham G., Liang, Dong, Hildebrandt, Michelle A. T., Wu, Xifeng, Levine, Douglas A., Bisogna, Maria, Berchuck, Andrew, Iversen, Edwin S., Schildkraut, Joellen M., Concannon, Patrick ORCID: 0000-0002-5801-1859, Weber, Rachel Palmieri, Cramer, Daniel W., Terry, Kathryn L., Poole, Elizabeth M., Tworoger, Shelley S., Bandera, Elisa V., Orlow, Irene ORCID: 0000-0001-6234-6961, Olson, Sara H., Krakstad, Camilla ORCID: 0000-0002-0174-8139, Salvesen, Helga B., Tangen, Ingvild L., Bjorge, Line ORCID: 0000-0002-0240-2770, van Altena, Anne M., Aben, Katja K. H., Kiemeney, Lambertus A. ORCID: 0000-0002-2368-1326, Massuger, Leon F. A. G., Kellar, Melissa, Brooks-Wilson, Angela ORCID: 0000-0003-1009-6408, Kelemen, Linda E., Cook, Linda S., Le, Nhu D., Cybulski, Cezary, Yang, Hannah, Lissowska, Jolanta ORCID: 0000-0003-2695-5799, Brinton, Louise A., Wentzensen, Nicolas, Hogdall, Claus ORCID: 0000-0002-5959-8874, Lundvall, Lene, Nedergaard, Lotte, Baker, Helen, Song, Honglin, Eccles, Diana ORCID: 0000-0002-9935-3169, McNeish, Ian, Paul, James ORCID: 0000-0001-7367-5816, Carty, Karen, Siddiqui, Nadeem, Glasspool, Rosalind ORCID: 0000-0002-5000-1680, Whittemore, Alice S., Rothstein, Joseph H., McGuire, Valerie, Sieh, Weiva, Ji, Bu-Tian, Zheng, Wei ORCID: 0000-0003-1226-070X, Shu, Xiao-Ou, Gao, Yu-Tang, Rosen, Barry, Risch, Harvey A., McLaughlin, John R., Narod, Steven A., Monteiro, Alvaro N., Chen, Ann, Lin, Hui-Yi ORCID: 0000-0002-3307-5549, Permuth-Wey, Jenny, Sellers, Thomas A., Tsai, Ya-Yu, Chen, Zhihua, Ziogas, Argyrios, Anton-Culver, Hoda, Gentry-Maharaj, Aleksandra, Menon, Usha ORCID: 0000-0003-3708-1732, Harrington, Patricia, Lee, Alice W., Wu, Anna H., Pearce, Celeste L., Coetzee, Gerry, Pike, Malcolm C., Dansonka-Mieszkowska, Agnieszka ORCID: 0000-0002-2482-6523, Timorek, Agnieszka, Rzepecka, Iwona K., Kupryjanczyk, Jolanta ORCID: 0000-0001-5820-0214, Freedman, Matt, Noushmehr, Houtan, Easton, Douglas F., Offit, Kenneth, Couch, Fergus J., Gayther, Simon, Pharoah, Paul P., Antoniou, Antonis C. and Chenevix-Trench, Georgia ORCID: 0000-0002-1878-2587 (2015). Identification of six new susceptibility loci for invasive epithelial ovarian cancer. Nature Genet., 47 (2). S. 164 - 172. NEW YORK: NATURE PUBLISHING GROUP. ISSN 1546-1718

Full text not available from this repository.

Abstract

Genome-wide association studies (GWAS) have identified 12 epithelial ovarian cancer (EOC) susceptibility alleles. The pattern of association at these loci is consistent in BRCA1 and BRCA2 mutation carriers who are at high risk of EOC. After imputation to 1000 Genomes Project data, we assessed associations of 11 million genetic variants with EOC risk from 15,437 cases unselected for family history and 30,845 controls and from 15,252 BRCA1 mutation carriers and 8,211 BRCA2 mutation carriers (3,096 with ovarian cancer), and we combined the results in a meta-analysis. This new study design yielded increased statistical power, leading to the discovery of six new EOC susceptibility loci. Variants at 1p36 (nearest gene, WNT4), 4q26 (SYNPO2), 9q34.2 (ABO) and 17q11.2 (ATAD5) were associated with EOC risk, and at 1p34.3 (RSPO1) and 6p22.1 (GPX6) variants were specifically associated with the serous EOC subtype, all with P < 5 x 10(-8). Incorporating these variants into risk assessment tools will improve clinical risk predictions for BRCA1 and BRCA2 mutation carriers.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Kuchenbaecker, Karoline B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ramus, Susan J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tyrer, JonathanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lee, AndrewUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Shen, Howard C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Beesley, JonathanUNSPECIFIEDorcid.org/0000-0003-1942-325XUNSPECIFIED
Lawrenson, KateUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
McGuffog, LesleyUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Healey, SueUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lee, Janet M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Spindler, Tassja J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lin, Yvonne G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pejovic, TanjaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bean, YukieUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Li, QiyuanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Coetzee, SimonUNSPECIFIEDorcid.org/0000-0003-4267-5930UNSPECIFIED
Hazelett, DennisUNSPECIFIEDorcid.org/0000-0003-0749-9935UNSPECIFIED
Miron, AlexanderUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Southey, MelissaUNSPECIFIEDorcid.org/0000-0002-6313-9005UNSPECIFIED
Terry, Mary BethUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Goldgar, David E.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Buys, Saundra S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Janavicius, RamunasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dorfling, Cecilia M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
van Rensburg, Elizabeth J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Neuhausen, Susan L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ding, Yuan ChunUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hansen, Thomas V. O.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jonson, LarsUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gerdes, Anne-MarieUNSPECIFIEDorcid.org/0000-0002-0328-3320UNSPECIFIED
Ejlertsen, BentUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Barrowdale, DanielUNSPECIFIEDorcid.org/0000-0003-1661-3939UNSPECIFIED
Dennis, JoeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Benitez, JavierUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Osorio, AnaUNSPECIFIEDorcid.org/0000-0001-8124-3984UNSPECIFIED
Garcia, Maria JoseUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Komenaka, IanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Weitzel, Jeffrey N.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ganschow, PamelaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Peterlongo, PaoloUNSPECIFIEDorcid.org/0000-0001-6951-6855UNSPECIFIED
Bernard, LorisUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Viel, AlessandraUNSPECIFIEDorcid.org/0000-0003-2804-0840UNSPECIFIED
Bonanni, BernardoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Peissel, BernardUNSPECIFIEDorcid.org/0000-0001-9233-3571UNSPECIFIED
Manoukian, SiranoushUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Radice, PaoloUNSPECIFIEDorcid.org/0000-0001-6298-4111UNSPECIFIED
Papi, LauraUNSPECIFIEDorcid.org/0000-0003-4552-9517UNSPECIFIED
Ottini, LauraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Fostira, FlorentiaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Konstantopoulou, IreneUNSPECIFIEDorcid.org/0000-0002-0470-0309UNSPECIFIED
Garber, JudyUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Frost, DebraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Perkins, JoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Platte, RadkaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ellis, SteveUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Godwin, Andrew K.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schmutzler, Rita KatharinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Meindl, AlfonsUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Engel, ChristophUNSPECIFIEDorcid.org/0000-0002-7247-282XUNSPECIFIED
Sutter, ChristianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sinilnikova, Olga M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Damiola, FrancescaUNSPECIFIEDorcid.org/0000-0002-0238-1252UNSPECIFIED
Mazoyer, SylvieUNSPECIFIEDorcid.org/0000-0002-2135-0160UNSPECIFIED
Stoppa-Lyonnet, DominiqueUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Claes, KathleenUNSPECIFIEDorcid.org/0000-0003-0841-7372UNSPECIFIED
De Leeneer, KimUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kirk, JudyUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rodriguez, Gustavo C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Piedmonte, MarionUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
O'Malley, David M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
de la Hoya, MiguelUNSPECIFIEDorcid.org/0000-0002-8113-1410UNSPECIFIED
Caldes, TrinidadUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Aittomaeki, KristiinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Nevanlinna, HeliUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Collee, J. MargrietUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rookus, Matti A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Oosterwijk, Jan C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tihomirova, LaimaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tung, NadineUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hamann, UteUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Isaccs, ClaudineUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tischkowitz, MarcUNSPECIFIEDorcid.org/0000-0002-7880-0628UNSPECIFIED
Imyanitov, Evgeny N.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Caligo, Maria A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Campbell, Ian G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hogervorst, Frans B. L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Olah, EdithUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Diez, OrlandUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Blanco, IgnacioUNSPECIFIEDorcid.org/0000-0002-7414-7481UNSPECIFIED
Brunet, JoanUNSPECIFIEDorcid.org/0000-0003-1945-3512UNSPECIFIED
Lazaroso, ConxiUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Angel Pujana, MiguelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jakubowska, AnnaUNSPECIFIEDorcid.org/0000-0002-5650-0501UNSPECIFIED
Gronwald, JacekUNSPECIFIEDorcid.org/0000-0002-3643-2871UNSPECIFIED
Lubinski, JanUNSPECIFIEDorcid.org/0000-0003-2931-3003UNSPECIFIED
Sukiennicki, GrzegorzUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Barkardottir, Rosa B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Plante, MarieUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Simard, JacquesUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Soucy, PennyUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Montagna, MarcoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tognazzo, SilviaUNSPECIFIEDorcid.org/0000-0002-6260-1261UNSPECIFIED
Teixeira, Manuel R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pankratz, Vernon S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wang, XianshuUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lindor, NoralaneUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Szabo, Csilla I.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kauff, NoahUNSPECIFIEDorcid.org/0000-0001-7242-6156UNSPECIFIED
Vijai, JosephUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Aghajanian, Carol A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pfeiler, GeorgUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Berger, AndreasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Singer, Christian F.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tea, Muy-KhengUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Phelan, Catherine M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Greene, Mark H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mai, Phuong L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rennert, GadUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mulligan, Anna MarieUNSPECIFIEDorcid.org/0000-0002-7239-5297UNSPECIFIED
Tchatchou, SandrineUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Andrulis, Irene L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Glendon, GordUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Toland, Amanda EwartUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jensen, Uffe BirkUNSPECIFIEDorcid.org/0000-0002-6205-6355UNSPECIFIED
Kruse, Torben A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Thomassen, MadsUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bojesen, AndersUNSPECIFIEDorcid.org/0000-0003-4289-8595UNSPECIFIED
Zidan, JamalUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Friedman, EitanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Laitman, YaelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Soller, MariaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Liljegren, AnnelieUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Arver, BritaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Einbeigi, ZakariaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stenmark-Askmalm, MarieUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Olopade, Olufunmilayo I.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Nussbaum, Robert L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rebbeck, Timothy R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Nathanson, Katherine L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Domchek, Susan M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lu, Karen H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Karlan, Beth Y.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Walsh, ChristineUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lester, JennyUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hein, AlexanderUNSPECIFIEDorcid.org/0000-0003-2601-3398UNSPECIFIED
Ekici, Arif B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Beckmann, Matthias W.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Fasching, Peter A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lambrechts, DietherUNSPECIFIEDorcid.org/0000-0002-3429-302XUNSPECIFIED
Van Nieuwenhuysen, ElsUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Vergote, IgnaceUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lambrechts, SandrinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dicks, EdUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Doherty, Jennifer A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wicklund, Kristine G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rossing, Mary AnneUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rudolph, AnjaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Chang-Claude, JennyUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wang-Gohrke, ShanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Eilber, UrsulaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Moysich, Kirsten B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Odunsi, KunleUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sucheston, LaraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lele, ShashiUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wilkens, Lynne R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Goodman, Marc T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Thompson, Pamela J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Shvetsov, Yurii B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Runnebaum, Ingo B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Duerst, MatthiasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hillemanns, PeterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Doerk, ThiloUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Antonenkova, NataliaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bogdanova, NataliaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Leminen, ArtoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pelttari, Liisa M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Butzow, RalfUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Modugno, FrancesmaryUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kelley, Joseph L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Edwards, Robert P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ness, Roberta B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
du Bois, AndreasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Heitz, FlorianUNSPECIFIEDorcid.org/0000-0002-2412-0352UNSPECIFIED
Schwaab, IraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Harter, PhilippUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Matsuo, KeitaroUNSPECIFIEDorcid.org/0000-0003-1761-6314UNSPECIFIED
Hosono, SatoyoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Orsulic, SandraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jensen, AllanUNSPECIFIEDorcid.org/0000-0001-8124-4880UNSPECIFIED
Kjaer, Susanne KrugerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hogdall, EstridUNSPECIFIEDorcid.org/0000-0003-4689-5658UNSPECIFIED
Hasmad, Hanis NazihahUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Azmi, Mat Adenan NoorUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Teo, Soo-HwangUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Woo, Yin-LingUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Fridley, Brooke L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Goode, Ellen L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cunningham, Julie M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Vierkant, Robert A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bruinsma, FionaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Giles, Graham G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Liang, DongUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hildebrandt, Michelle A. T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wu, XifengUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Levine, Douglas A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bisogna, MariaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Berchuck, AndrewUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Iversen, Edwin S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schildkraut, Joellen M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Concannon, PatrickUNSPECIFIEDorcid.org/0000-0002-5801-1859UNSPECIFIED
Weber, Rachel PalmieriUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cramer, Daniel W.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Terry, Kathryn L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Poole, Elizabeth M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tworoger, Shelley S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bandera, Elisa V.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Orlow, IreneUNSPECIFIEDorcid.org/0000-0001-6234-6961UNSPECIFIED
Olson, Sara H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Krakstad, CamillaUNSPECIFIEDorcid.org/0000-0002-0174-8139UNSPECIFIED
Salvesen, Helga B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tangen, Ingvild L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bjorge, LineUNSPECIFIEDorcid.org/0000-0002-0240-2770UNSPECIFIED
van Altena, Anne M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Aben, Katja K. H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kiemeney, Lambertus A.UNSPECIFIEDorcid.org/0000-0002-2368-1326UNSPECIFIED
Massuger, Leon F. A. G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kellar, MelissaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Brooks-Wilson, AngelaUNSPECIFIEDorcid.org/0000-0003-1009-6408UNSPECIFIED
Kelemen, Linda E.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cook, Linda S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Le, Nhu D.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cybulski, CezaryUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Yang, HannahUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lissowska, JolantaUNSPECIFIEDorcid.org/0000-0003-2695-5799UNSPECIFIED
Brinton, Louise A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wentzensen, NicolasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hogdall, ClausUNSPECIFIEDorcid.org/0000-0002-5959-8874UNSPECIFIED
Lundvall, LeneUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Nedergaard, LotteUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Baker, HelenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Song, HonglinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Eccles, DianaUNSPECIFIEDorcid.org/0000-0002-9935-3169UNSPECIFIED
McNeish, IanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Paul, JamesUNSPECIFIEDorcid.org/0000-0001-7367-5816UNSPECIFIED
Carty, KarenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Siddiqui, NadeemUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Glasspool, RosalindUNSPECIFIEDorcid.org/0000-0002-5000-1680UNSPECIFIED
Whittemore, Alice S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rothstein, Joseph H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
McGuire, ValerieUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sieh, WeivaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ji, Bu-TianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Zheng, WeiUNSPECIFIEDorcid.org/0000-0003-1226-070XUNSPECIFIED
Shu, Xiao-OuUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gao, Yu-TangUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rosen, BarryUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Risch, Harvey A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
McLaughlin, John R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Narod, Steven A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Monteiro, Alvaro N.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Chen, AnnUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lin, Hui-YiUNSPECIFIEDorcid.org/0000-0002-3307-5549UNSPECIFIED
Permuth-Wey, JennyUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sellers, Thomas A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tsai, Ya-YuUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Chen, ZhihuaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ziogas, ArgyriosUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Anton-Culver, HodaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gentry-Maharaj, AleksandraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Menon, UshaUNSPECIFIEDorcid.org/0000-0003-3708-1732UNSPECIFIED
Harrington, PatriciaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lee, Alice W.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wu, Anna H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pearce, Celeste L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Coetzee, GerryUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pike, Malcolm C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dansonka-Mieszkowska, AgnieszkaUNSPECIFIEDorcid.org/0000-0002-2482-6523UNSPECIFIED
Timorek, AgnieszkaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rzepecka, Iwona K.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kupryjanczyk, JolantaUNSPECIFIEDorcid.org/0000-0001-5820-0214UNSPECIFIED
Freedman, MattUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Noushmehr, HoutanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Easton, Douglas F.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Offit, KennethUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Couch, Fergus J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gayther, SimonUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pharoah, Paul P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Antoniou, Antonis C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Chenevix-Trench, GeorgiaUNSPECIFIEDorcid.org/0000-0002-1878-2587UNSPECIFIED
URN: urn:nbn:de:hbz:38-414106
DOI: 10.1038/ng.3185
Journal or Publication Title: Nature Genet.
Volume: 47
Number: 2
Page Range: S. 164 - 172
Date: 2015
Publisher: NATURE PUBLISHING GROUP
Place of Publication: NEW YORK
ISSN: 1546-1718
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
BRCA2 MUTATION CARRIERS; SINGLE NUCLEOTIDE POLYMORPHISMS; GENOME-WIDE ASSOCIATION; ABO BLOOD-GROUP; BREAST-CANCER; COMMON VARIANTS; HUMAN ELG1; HIGH-RISK; MYOPODIN; METAANALYSISMultiple languages
Genetics & HeredityMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/41410

Downloads

Downloads per month over past year

Altmetric

Export

Actions (login required)

View Item View Item