Universität zu Köln

Herden, Jan ORCID: 0000-0002-1667-5200, Eminaga, Okyaz, Wille, Sebastian and Weissbach, Lothar (2015). Treatment of Incidental Prostate Cancer by Active Surveillance: Results of the HAROW Study. Urol.Int., 95 (2). S. 209 - 216. BASEL: KARGER. ISSN 1423-0399

Full text not available from this repository.

Abstract

Objective: To report on a cohort of patients with incidental prostate cancer (IPC) that was treated by an active surveillance (AS) protocol in the HAROW study. Materials and Methods: The HAROW study is an observational study on the management of localized prostate cancer in Germany. Treating urologists were reporting clinical parameters, information on therapy and clinical course of disease at 6-month intervals. Results: In total, 3,169 patients were enrolled. In 224 patients were found an IPC and 104 (46%) of them were put on an AS protocol. The mean follow-up was 26.5 months. Tumor progression was noted in 16 patients. In 11 patients, AS was replaced by a definite intervention. In univariate and multivariate analyses, only PSA density correlated with progression. Conclusion: This is the first prospective description of an IPC patient cohort on AS as part of an outcomes research study. AS was selected as a therapeutic strategy in nearly half of the patients (46%). Only a minor proportion (16%) displayed progression. Of the clinical parameters, only PSA density correlated with progression. (C) 2015 S. Karger AG, Basel

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Herden, Jan UNSPECIFIED orcid.org/0000-0002-1667-5200 UNSPECIFIED Eminaga, Okyaz UNSPECIFIED UNSPECIFIED UNSPECIFIED Wille, Sebastian UNSPECIFIED UNSPECIFIED UNSPECIFIED Weissbach, Lothar UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-416002
DOI:	10.1159/000431024
Journal or Publication Title:	Urol.Int.
Volume:	95
Number:	2
Page Range:	S. 209 - 216
Date:	2015
Publisher:	KARGER
Place of Publication:	BASEL
ISSN:	1423-0399
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language RADICAL PROSTATECTOMY; TRANSURETHRAL RESECTION; BIOCHEMICAL RECURRENCE; STAGE T1A; PSA ERA; CARCINOMA; EXTENT; PROBABILITY; PROGRESSION; PREDICTORS Multiple languages Urology & Nephrology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/41600