Universität zu Köln

Noe, Guenter-Karl, Anapolski, Michael, Soltesz, Stefan, Spuentrup, Carolin, Mettler, Liselotte, Schollmeyer, Thoralf and Alkatout, Ibrahim (2015). Value of Clinical and Laboratory Inflammation Factors in the Postoperative Period after Laparoscopic Urogynecological Surgery. Gynecol.Obstet.Invest., 79 (1). S. 57 - 62. BASEL: KARGER. ISSN 1423-002X

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Abstract

Background/Aims: Leukocytes and C-reactive protein (CRP) levels are often used to detect infections. The aim of this study was to evaluate the diagnostic and screening validity of leukocytes and CRP levels as well as body temperature >38 degrees C to predict infections after laparoscopic sacrocolpopexy. Methods: The study included 287 patients suffering from genital prolapse higher than POP-Q I. In addition to the sacrocolpopexy, a laparoscopic supracervical hysterectomy was performed in cases of preexisting uterus (n = 171). Leukocytes and CRP levels were analyzed preoperatively and 4 days after surgery. Early and late onset of infections was documented. Results: Urinary tract infection was identified as the most frequent early postoperative complication (11.4%). Early wound infections were found in 2.8% of the patients (8/287). Late onset of infections was found in 1% of patients (3/287). Areas under ROC curves were low for both leukocytes (0.52, 95% CI: 0.37-0.66) and CRP levels (0.60, 95% CI: 0.44-0.77). Conclusion: Our findings question the benefit of routine determination of leukocytes and CRP levels 4 days after surgery. The sensitivity and specificity of leukocytes and CRP levels are probably more significant after normalization of the initial tissue response (days 8-10). (C) 2014 S. Karger AG, Basel

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Noe, Guenter-Karl UNSPECIFIED UNSPECIFIED UNSPECIFIED Anapolski, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Soltesz, Stefan UNSPECIFIED UNSPECIFIED UNSPECIFIED Spuentrup, Carolin UNSPECIFIED UNSPECIFIED UNSPECIFIED Mettler, Liselotte UNSPECIFIED UNSPECIFIED UNSPECIFIED Schollmeyer, Thoralf UNSPECIFIED UNSPECIFIED UNSPECIFIED Alkatout, Ibrahim UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-417724
DOI:	10.1159/000364868
Journal or Publication Title:	Gynecol.Obstet.Invest.
Volume:	79
Number:	1
Page Range:	S. 57 - 62
Date:	2015
Publisher:	KARGER
Place of Publication:	BASEL
ISSN:	1423-002X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language C-REACTIVE PROTEIN; PLASMA-CONCENTRATIONS; COLORECTAL-CANCER; COMPLICATIONS; RESECTION; INJURY; PROCALCITONIN; PREDICTOR; TISSUE Multiple languages Obstetrics & Gynecology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/41772