Universität zu Köln

Ulrich, Anne, Burg, Matthias C., Raupach, Rainer, Bunck, Alexander, Schuelke, Christoph, Maintz, David, Heindel, Walter and Seifarth, Harald (2015). Coronary stent imaging with dual-source CT: assessment of lumen visibility using different convolution kernels and postprocessing filters. Acta Radiol., 56 (1). S. 42 - 51. LONDON: SAGE PUBLICATIONS LTD. ISSN 1600-0455

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Abstract

Background: Assesment of the coronary arteries after stent placement using coronary computed tomography angiography (CCTA) currently requires reconstruction of images with soft kernels for the assessment of atherosclerotic plaques and dedicated edge enhancing kernels for the evaluation of the stent lumen. Purpose: To evaluate a two-dimensional filter tool that provides instant postprocessing of images reconstructed with soft kernels into edge-enhanced images and vice versa and thus may eliminate the need for two separate reconstrcutions for the assessment of coronary artery stents using CCTA. Material and Methods: Twenty stents with a diameter of 3.0 mm placed in a vascular phantom were scanned with a dual-source CT using standard parameters. Images were reconstructed with a soft B30f and an edge-enhancing B46f kernel and postprocessed with the corresponding filter algorithm (F30 for B30f images; F46 for B46f images). The resulting four datasets were evaluated for lumen visibility, intraluminal attenuation, and image noise by two independent readers. Results were validated in vivo against invasive coronary angiography in data-sets from patients with coronary artery stents. Results: Average intraluminal attenuation was 552.6 HU, 527.3 HU, 207.9 HU, and 267.5 HU for B30f, F30, B46f, and F46 images, respectively (P < 0.0001). Average image noise was 11.3, 10.6, 19.2, and 15.0 HU, respectively (P < 0.0001). The visible stent diameter was significantly higher in the B46f (59.6%) and F46 images (54%) compared to the B30f (48.3%) and F30 (51.5%) images (P < 0.0001). In the patient study, lumen assessability was significantly better in B46f images than in F46 images. Sensitivity for stenosis detection was best in the original B46f images with a sensitivity of 67% and a specificity of 94%. Conclusion: The postprocessing filter reduces image noise, however currently it does not offer an alternative to image reconstruction using the edge-enhancing kernels for the evaluation of the stent lumen.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Ulrich, Anne UNSPECIFIED UNSPECIFIED UNSPECIFIED Burg, Matthias C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Raupach, Rainer UNSPECIFIED UNSPECIFIED UNSPECIFIED Bunck, Alexander UNSPECIFIED UNSPECIFIED UNSPECIFIED Schuelke, Christoph UNSPECIFIED UNSPECIFIED UNSPECIFIED Maintz, David UNSPECIFIED UNSPECIFIED UNSPECIFIED Heindel, Walter UNSPECIFIED UNSPECIFIED UNSPECIFIED Seifarth, Harald UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-418135
DOI:	10.1177/0284185113517229
Journal or Publication Title:	Acta Radiol.
Volume:	56
Number:	1
Page Range:	S. 42 - 51
Date:	2015
Publisher:	SAGE PUBLICATIONS LTD
Place of Publication:	LONDON
ISSN:	1600-0455
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language MULTISLICE COMPUTED-TOMOGRAPHY; ARTERY-DISEASE; ELUTING STENT; ANGIOGRAPHY; VISUALIZATION; PACLITAXEL; EXPERIENCE Multiple languages Radiology, Nuclear Medicine & Medical Imaging Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/41813