Universität zu Köln

Schroeder, W., Leers, J. M., Bludau, M., Herbold, T. and Holscher, A. H. (2014). Perforations near the cardia in benign diseases. Chirurg, 85 (12). S. 1064 - 1071. NEW YORK: SPRINGER. ISSN 1433-0385

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Abstract

Esophageal perforations nearby the cardia are a clinical disorder of various causes. Perforations occur most often following diagnostic or interventional endoscopy but spontaneous perforations (Boerhaave syndrome) are less frequent. Due to the heterogeneous etiology there is a broad range of therapeutic options. In most cases the esophageal perforation site can be covered by an endoscopic stent. Recent endoscopic procedures are the intraluminal application of an endoscopic vacuum-assisted closure system (endo-VAC) or clipping of the esophageal defect. Surgical procedures include direct suturing with external coverage of the defect or transhiatal blunt dissection of the esophagus without primary reconstruction. All endoscopic and surgical procedures often require an additional drainage of the mediastinum and if necessary of the thoracic and abdominal cavities. The clinical presentation ranges from a simple perforation without concomitant esophageal pathology to a defect of considerable length with pleural perforation and associated septic multiple organ failure. The severity of the septic course is the crucial parameter for the choice of the procedure. An early multiple organ failure indicates an insufficient drainage of the septic focus and is indicative for surgical resection. The overall mortality is given as 12 % in the current literature and primarily depends on the localization and the etiology of the perforation. The highest mortality rates are observed with Boerhaave syndrome. The most important prognostic variable is the time interval between perforation and initiation of therapy whereby the mortality rises up to 20 % if the interval exceeds 24 h. Due to the complex therapy and the poor prognosis esophageal perforations should be treated in specialized centers.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Schroeder, W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Leers, J. M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Bludau, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Herbold, T. UNSPECIFIED UNSPECIFIED UNSPECIFIED Holscher, A. H. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-421547
DOI:	10.1007/s00104-014-2805-z
Journal or Publication Title:	Chirurg
Volume:	85
Number:	12
Page Range:	S. 1064 - 1071
Date:	2014
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1433-0385
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ESOPHAGEAL-PERFORATION; ANASTOMOTIC LEAK; COMPUTED-TOMOGRAPHY; CONTRAST SWALLOW; MANAGEMENT; IMPACT; SURGERY; OPTIONS; CLOSURE; ADULTS Multiple languages Surgery Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/42154