Universität zu Köln

Kraemer, Christiane, Jaspers, Natalie, Nierhoff, Dirk, Kuhr, Kathrin, Bowe, Andrea, Goeser, Tobias and Michels, Guido (2014). ACOUSTIC STRUCTURE QUANTIFICATION ULTRASOUND SOFTWARE PROVES IMPRECISE IN ASSESSING LIVER FIBROSIS OR CIRRHOSIS IN PARENCHYMAL LIVER DISEASES. Ultrasound Med. Biol., 40 (12). S. 2811 - 2819. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1879-291X

Full text not available from this repository.

Abstract

The present study was conducted to assess the diagnostic accuracy of Acoustic Structure Quantification (ASQ) ultrasound software in liver biopsy of patients with liver fibrosis and cirrhosis. Eighty patients (47 +/- 14 y, 41 men) with chronic liver diseases underwent ultrasound examination of the liver and liver biopsy. In addition to the standard-care ultrasound examination, three valid gray-scale images were obtained for each patient. With the ASQ software, the average and peak values (C-m(2)) of each ultrasound gray-scale image were calculated and then compared with histologic fibrosis staging (F0-F4). No correlation was found between ASQ values and histologic fibrosis stage (p > 0.05). Areas under the curve for the diagnosis of no or mild fibrosis (F0 and F1), moderate/severe fibrosis (F2 and F3) and cirrhosis (F4) using average/peak C-m(2) values of small regions of interest were 0.46/0.43, 0.62/0.68 and 0.38/0.33. Determination of liver fibrosis with ASQ in its present form as an alternative approach to liver biopsy is too imprecise. (C) 2014 World Federation for Ultrasound in Medicine & Biology.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Kraemer, Christiane UNSPECIFIED UNSPECIFIED UNSPECIFIED Jaspers, Natalie UNSPECIFIED UNSPECIFIED UNSPECIFIED Nierhoff, Dirk UNSPECIFIED UNSPECIFIED UNSPECIFIED Kuhr, Kathrin UNSPECIFIED UNSPECIFIED UNSPECIFIED Bowe, Andrea UNSPECIFIED UNSPECIFIED UNSPECIFIED Goeser, Tobias UNSPECIFIED UNSPECIFIED UNSPECIFIED Michels, Guido UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-421918
DOI:	10.1016/j.ultrasmedbio.2014.07.020
Journal or Publication Title:	Ultrasound Med. Biol.
Volume:	40
Number:	12
Page Range:	S. 2811 - 2819
Date:	2014
Publisher:	ELSEVIER SCIENCE INC
Place of Publication:	NEW YORK
ISSN:	1879-291X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language RADIATION FORCE IMPULSE; TRANSIENT ELASTOGRAPHY; CHRONIC HEPATITIS Multiple languages Acoustics; Radiology, Nuclear Medicine & Medical Imaging Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/42191