Universität zu Köln

Koprivova, Anna and Kopriva, Stanislav ORCID: 0000-0002-7416-6551 (2014). Molecular mechanisms of regulation of sulfate assimilation: first steps on a long road. Front. Plant Sci., 5. LAUSANNE: FRONTIERS MEDIA SA. ISSN 1664-462X

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Abstract

The pathway of sulfate assimilation, which provides plants with the essential nutrient sulfur, is tightly regulated and coordinated with the demand for reduced sulfur. The responses of metabolite concentrations, enzyme activities and mRNA levels to various signals and environmental conditions have been well described for the pathway. However, only little is known about the molecular mechanisms of this regulation. To date, nine transcription factors have been described to control transcription of genes of sulfate uptake and assimilation. In addition, other levels of regulation contribute to the control of sulfur metabolism. Post-transcriptional regulation has been shown for sulfate transporters, adenosine 5'phosphosulfate reductase, and cysteine synthase. Several genes of the pathway are targets of microRNA miR395. In addition, protein protein interaction is increasingly found in the center of various regulatory circuits. On top of the mechanisms of regulation of single genes, we are starting to learn more about mechanisms of adaptation, due to analyses of natural variation. In this article, the summary of different mechanisms of regulation will be accompanied by identification of the major gaps in knowledge and proposition of possible ways of filling them.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Koprivova, Anna UNSPECIFIED UNSPECIFIED UNSPECIFIED Kopriva, Stanislav UNSPECIFIED orcid.org/0000-0002-7416-6551 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-425462
DOI:	10.3389/fpls.2014.00589
Journal or Publication Title:	Front. Plant Sci.
Volume:	5
Date:	2014
Publisher:	FRONTIERS MEDIA SA
Place of Publication:	LAUSANNE
ISSN:	1664-462X
Language:	English
Faculty:	Faculty of Mathematics and Natural Sciences
Divisions:	Faculty of Mathematics and Natural Sciences > Department of Biology > Botanical Institute
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ADENOSINE 5'-PHOSPHOSULFATE REDUCTASE; CYSTEINE SYNTHASE COMPLEX; GAMMA-GLUTAMYLCYSTEINE SYNTHETASE; ACETYLSERINE THIOL LYASE; ARABIDOPSIS-THALIANA; O-ACETYLSERINE; HYDROGEN-SULFIDE; ATP SULFURYLASE; GLUCOSINOLATE BIOSYNTHESIS; SERINE ACETYLTRANSFERASE Multiple languages Plant Sciences Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/42546