Universität zu Köln

Koehler, Philipp ORCID: 0000-0002-7386-7495, Tacke, Daniela and Cornely, Oliver A. (2014). Our 2014 approach to candidaemia. Mycoses, 57 (10). S. 581 - 584. HOBOKEN: WILEY. ISSN 1439-0507

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Abstract

Candidaemia remains a relevant challenge in everyday patient care on intensive care units and general wards. Delays to adequate treatment increase mortality rates and institutional standard operating procedures facilitate optimal treatment. A positive blood culture requires immediate treatment. Echinocandins are the first-line drugs of choice. Indwelling catheters have to be removed if feasible. Daily blood cultures until persistently negative exclude ongoing fungaemia. In case of Candida parapsilosis antifungal therapy should be switched to intravenous fluconazole. After 10days of intravenous either echinocandin or fluconazole treatment, step-down to oral application of fluconazole simplifies antifungal therapy. Depending on organ involvement and clinical presentation of the patient antifungal treatment should be continued for at least 14days after the last positive blood culture. We present our institutional management algorithm for candidaemia which is based on current guidelines and recommendations to improve patient outcome.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Koehler, Philipp UNSPECIFIED orcid.org/0000-0002-7386-7495 UNSPECIFIED Tacke, Daniela UNSPECIFIED UNSPECIFIED UNSPECIFIED Cornely, Oliver A. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-427770
DOI:	10.1111/myc.12207
Journal or Publication Title:	Mycoses
Volume:	57
Number:	10
Page Range:	S. 581 - 584
Date:	2014
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1439-0507
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ESCMID-ASTERISK GUIDELINE; BLOOD-STREAM INFECTION; ANTIFUNGAL SUSCEPTIBILITY; NOSOCOMIAL CANDIDEMIA; INVASIVE CANDIDIASIS; FUNGAL-INFECTIONS; RISK-FACTORS; EPIDEMIOLOGY; FLUCONAZOLE; MANAGEMENT Multiple languages Dermatology; Mycology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/42777