Universität zu Köln

Sansone, Alfredo ORCID: 0000-0002-1197-7322, Syed, Adnan S., Tantalaki, Evangelia, Korsching, Sigrun I. ORCID: 0000-0002-5450-172X and Manzini, Ivan ORCID: 0000-0002-3575-9637 (2014). Trpc2 is expressed in two olfactory subsystems, the main and the vomeronasal system of larval Xenopus laevis. J. Exp. Biol., 217 (13). S. 2235 - 2239. CAMBRIDGE: COMPANY BIOLOGISTS LTD. ISSN 1477-9145

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Abstract

Complete segregation of the main olfactory epithelium (MOE) and the vomeronasal epithelium is first observed in amphibians. In contrast, teleost fishes possess a single olfactory surface, in which genetic components of the main and vomeronasal olfactory systems are intermingled. The transient receptor potential channel TRPC2, a marker of vomeronasal neurons, is present in the single fish sensory surface, but is already restricted to the vomeronasal epithelium in a terrestrial amphibian, the red-legged salamander (Plethodon shermani). Here we examined the localization of TRPC2 in an aquatic amphibian and cloned the Xenopus laevis trpc2 gene. We show that it is expressed in both the MOE and the vomeronasal epithelium. This is the first description of a broad trpc2 expression in the MOE of a tetrapod. The expression pattern of trpc2 in the MOE is virtually undistinguishable from that of MOE-specific v2rs, indicating that they are co-expressed in the same neuronal subpopulation.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Sansone, Alfredo UNSPECIFIED orcid.org/0000-0002-1197-7322 UNSPECIFIED Syed, Adnan S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Tantalaki, Evangelia UNSPECIFIED UNSPECIFIED UNSPECIFIED Korsching, Sigrun I. UNSPECIFIED orcid.org/0000-0002-5450-172X UNSPECIFIED Manzini, Ivan UNSPECIFIED orcid.org/0000-0002-3575-9637 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-434526
DOI:	10.1242/jeb.103465
Journal or Publication Title:	J. Exp. Biol.
Volume:	217
Number:	13
Page Range:	S. 2235 - 2239
Date:	2014
Publisher:	COMPANY BIOLOGISTS LTD
Place of Publication:	CAMBRIDGE
ISSN:	1477-9145
Language:	English
Faculty:	Faculty of Mathematics and Natural Sciences
Divisions:	Faculty of Mathematics and Natural Sciences > Department of Biology > Institute for Genetics
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language Biology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/43452