Universität zu Köln

Drzezga, Alexander, Barthel, Henryk, Minoshima, Satoshi ORCID: 0000-0002-0043-3047 and Sabri, Osama ORCID: 0000-0002-6425-3504 (2014). Potential Clinical Applications of PET/MR Imaging in Neurodegenerative Diseases. J. Nucl. Med., 55. S. 47S - 56. RESTON: SOC NUCLEAR MEDICINE INC. ISSN 1535-5667

Full text not available from this repository.

Abstract

Neurodegenerative disorders such as Alzheimer disease are among today's most alarming health problems in our aging society. The clinical assessment of neurodegenerative disorders benefits from recent innovations in the field of imaging technology. These innovations include emerging tracers for molecular imaging of neurodegenerative pathology and the introduction of novel integrated PET/MR imaging instruments. Because both PET and MR imaging procedures have shown critical value in the diagnostic work-up of neurodegenerative disorders, the combination of both imaging modalities in the form of an integrated PET/MR imaging system may be of value. This combination includes practical methodologic advantages and an improved workflow facilitated by the combined acquisition of dual-modality data. It offers clinical advantages because of the systematic combination of complementary information, potentially allowing the creation of novel integrated imaging biomarkers. The effectiveness of new disease-modifying treatments may depend on the timely initiation of therapy before irreversible neuronal damage in slowly progressive neurodegenerative disorders. Integrated PET/MR imaging may be able to improve such early diagnosis through both structural and functional information.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Drzezga, Alexander UNSPECIFIED UNSPECIFIED UNSPECIFIED Barthel, Henryk UNSPECIFIED UNSPECIFIED UNSPECIFIED Minoshima, Satoshi UNSPECIFIED orcid.org/0000-0002-0043-3047 UNSPECIFIED Sabri, Osama UNSPECIFIED orcid.org/0000-0002-6425-3504 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-437066
DOI:	10.2967/jnumed.113.129254
Journal or Publication Title:	J. Nucl. Med.
Volume:	55
Page Range:	S. 47S - 56
Date:	2014
Publisher:	SOC NUCLEAR MEDICINE INC
Place of Publication:	RESTON
ISSN:	1535-5667
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language POSITRON-EMISSION-TOMOGRAPHY; MILD COGNITIVE IMPAIRMENT; ALZHEIMERS ASSOCIATION WORKGROUPS; FDG-PET; DIAGNOSTIC GUIDELINES; NATIONAL INSTITUTE; NONDEMENTED INDIVIDUALS; DIFFERENTIAL-DIAGNOSIS; ATTENUATION CORRECTION; HYPOTHETICAL MODEL Multiple languages Radiology, Nuclear Medicine & Medical Imaging Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/43706