Universität zu Köln

Braehler, Sebastian, Thielen, Indra, Schwabe, Hendrik, Engels, Marianne, Kreuzer, Karl-Anton, Wolf, Juergen and Ansen, Sascha (2014). Rapid remineralization of multiple disseminated bone lesions after high-dose cytarabine in a patient with isolated myeloid sarcoma. Eur. J. Haematol., 92 (6). S. 537 - 541. HOBOKEN: WILEY-BLACKWELL. ISSN 1600-0609

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Abstract

Isolated myeloid sarcoma is a rare presentation of acute myeloid leukemia. There are limited data available concerning the prognostic relevance and the right treatment strategy for this clinical scenario. Here, we report a case of acute myeloid leukemia with extensive lesions and fractures in multiple bones in a 64-yr-old male patient. Remarkably, treatment with a high-dose cytarabine regimen led to rapid remineralization of all bone lesions and recovery of the patient's mobility within a few weeks. Thereby, surgical treatment and radiotherapy could be avoided, supporting the role of intensive induction and standard consolidation chemotherapy as first-line treatment for myeloid sarcoma.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Braehler, Sebastian UNSPECIFIED UNSPECIFIED UNSPECIFIED Thielen, Indra UNSPECIFIED UNSPECIFIED UNSPECIFIED Schwabe, Hendrik UNSPECIFIED UNSPECIFIED UNSPECIFIED Engels, Marianne UNSPECIFIED UNSPECIFIED UNSPECIFIED Kreuzer, Karl-Anton UNSPECIFIED UNSPECIFIED UNSPECIFIED Wolf, Juergen UNSPECIFIED UNSPECIFIED UNSPECIFIED Ansen, Sascha UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-437155
DOI:	10.1111/ejh.12254
Journal or Publication Title:	Eur. J. Haematol.
Volume:	92
Number:	6
Page Range:	S. 537 - 541
Date:	2014
Publisher:	WILEY-BLACKWELL
Place of Publication:	HOBOKEN
ISSN:	1600-0609
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language GRANULOCYTIC SARCOMA; LEUKEMIA; ADULTS Multiple languages Hematology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/43715