Universität zu Köln

Arendrup, M. C., Boekhout, T., Akova, M., Meis, J. F., Cornely, O. A. and Lortholary, O. (2014). ESCMID dagger and ECMM double dagger joint clinical guidelines for the diagnosis and management of rare invasive yeast infections. Clin. Microbiol. Infect., 20. S. 76 - 99. OXFORD: ELSEVIER SCI LTD. ISSN 1469-0691

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Abstract

The mortality associated with invasive fungal infections remains high with that involving rare yeast pathogens other than Candida being no exception. This is in part due to the severe underlying conditions typically predisposing patients to these healthcare-related infections (most often severe neutropenia in patients with haematological malignancies), and in part due to the often challenging intrinsic susceptibility pattern of the pathogens that potentially leads to delayed appropriate antifungal treatment. A panel of experts of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Fungal Infection Study Group (EFISG) and the European Confederation of Medical Mycology (ECMM) undertook a data review and compiled guidelines for the diagnostic tests and procedures for detection and management of rare invasive yeast infections. The rare yeast pathogens were defined and limited to the following genera/species: Cryptococcus adeliensis, Cryptococcus albidus, Cryptococcus curvatus, Cryptococcus flavescens, Cryptococcus laurentii and Cryptococcus uniguttulatus (often published under the name Filobasidium uniguttulatum), Malassezia furfur, Malassezia globosa, Malassezia pachydermatis and Malassezia restricta, Pseudozyma spp., Rhodotorula glutinis, Rhodotorula minuta and Rhodotorula mucilaginosa, Sporobolomyces spp., Trichosporon asahii, Trichosporon asteroides, Trichosporon dermatis, Trichosporon inkin, Trichosporon jirovecii, Trichosporon loubieri, Trichosporon mucoides and Trichosporon mycotoxinivorans and ascomycetous ones: Geotrichum candidum, Kodamaea ohmeri, Saccharomyces cerevisiae (incl. S.boulardii) and Saprochaete capitatae (Magnusiomyces (Blastoschizomyces) capitatus formerly named Trichosporon capitatum or Geotrichum (Dipodascus) capitatum) and Saprochaete clavata. Recommendations about the microbiological investigation and detection of invasive infection were made and current knowledge on the most appropriate antifungal and supportive treatment was reviewed. In addition, remarks about antifungal susceptibility testing were made.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Arendrup, M. C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Boekhout, T. UNSPECIFIED UNSPECIFIED UNSPECIFIED Akova, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Meis, J. F. UNSPECIFIED UNSPECIFIED UNSPECIFIED Cornely, O. A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Lortholary, O. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-442100
DOI:	10.1111/1469-0691.12360
Journal or Publication Title:	Clin. Microbiol. Infect.
Volume:	20
Page Range:	S. 76 - 99
Date:	2014
Publisher:	ELSEVIER SCI LTD
Place of Publication:	OXFORD
ISSN:	1469-0691
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language INTENSIVE-CARE-UNIT; BLASTOSCHIZOMYCES-CAPITATUS INFECTION; SACCHAROMYCES-CEREVISIAE FUNGEMIA; DESORPTION IONIZATION-TIME; STEM-CELL TRANSPLANTATION; PICHIA OHMERI FUNGEMIA; ACUTE MYELOID-LEUKEMIA; ANTIFUNGAL SUSCEPTIBILITY PROFILE; TRICHOSPORON-ASAHII FUNGEMIA; LIPOSOMAL AMPHOTERICIN-B Multiple languages Infectious Diseases; Microbiology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/44210