Universität zu Köln

Zevnik, Branko ORCID: 0000-0001-7845-9522, Uyttersprot, Nathalie C., Perez, Ana V., Bothe, Gerald W. M., Kern, Heidrun and Kauselmann, Gunther (2014). C57BL/6N Albino/Agouti Mutant Mice as Embryo Donors for Efficient Germline Transmission of C57BL/6 ES Cells. PLoS One, 9 (3). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203

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Abstract

We generated C57BL/6NTac mice carrying a tyrosinase loss-of function mutation and a reversion of the nonagouti locus to agouti. This strain has a high superovulation response, allows visual detection of chimeric coat color contribution of C57BL/6 ES-cells and provides a simplified breeding format that generates black G1 offspring of pure inbred C57BL/6 background in one step, providing the ideal host for genetically manipulated C57BL/6 ES cells.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Zevnik, Branko UNSPECIFIED orcid.org/0000-0001-7845-9522 UNSPECIFIED Uyttersprot, Nathalie C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Perez, Ana V. UNSPECIFIED UNSPECIFIED UNSPECIFIED Bothe, Gerald W. M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Kern, Heidrun UNSPECIFIED UNSPECIFIED UNSPECIFIED Kauselmann, Gunther UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-443534
DOI:	10.1371/journal.pone.0090570
Journal or Publication Title:	PLoS One
Volume:	9
Number:	3
Date:	2014
Publisher:	PUBLIC LIBRARY SCIENCE
Place of Publication:	SAN FRANCISCO
ISSN:	1932-6203
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language IMPROVED GENERATION; BALB/C BLASTOCYSTS; STEM-CELLS; MOUSE; ESTABLISHMENT; GENE; LINE; TYROSINASE Multiple languages Multidisciplinary Sciences Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/44353