Universität zu Köln

Gazzinelli, Ricardo T., Mendonca-Neto, Rondon, Lilue, Jingtao ORCID: 0000-0002-1958-0231, Howard, Jonathan ORCID: 0000-0003-2756-5143 and Sher, Alan (2014). Innate Resistance against Toxoplasma gondii: An Evolutionary Tale of Mice, Cats, and Men. Cell Host Microbe, 15 (2). S. 132 - 139. CAMBRIDGE: CELL PRESS. ISSN 1934-6069

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Abstract

Recent studies have revealed remarkable species specificity of the Toll-like receptors (TLRs) TLR11 and TLR12 and the immunity-related GTPase (IRG) proteins that are essential elements for detection and immune control of Toxoplasma gondii in mice, but not in humans. The biological and evolutionary implications of these findings for the T. gondii host-pathogen relationship and for human disease are discussed.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Gazzinelli, Ricardo T. UNSPECIFIED UNSPECIFIED UNSPECIFIED Mendonca-Neto, Rondon UNSPECIFIED UNSPECIFIED UNSPECIFIED Lilue, Jingtao UNSPECIFIED orcid.org/0000-0002-1958-0231 UNSPECIFIED Howard, Jonathan UNSPECIFIED orcid.org/0000-0003-2756-5143 UNSPECIFIED Sher, Alan UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-445918
DOI:	10.1016/j.chom.2014.01.004
Journal or Publication Title:	Cell Host Microbe
Volume:	15
Number:	2
Page Range:	S. 132 - 139
Date:	2014
Publisher:	CELL PRESS
Place of Publication:	CAMBRIDGE
ISSN:	1934-6069
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language DENDRITIC CELLS; PROFILIN; IMMUNITY; MECHANISM; MONOCYTES; INFECTION; VIRULENCE; GTPASES Multiple languages Microbiology; Parasitology; Virology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/44591