Universität zu Köln

Kaya, Yasemin, Ozsoy, Umut, Turhan, Murat ORCID: 0000-0001-6140-1666, Angelov, Doychin N. and Sarikcioglu, Levent ORCID: 0000-0002-0825-6225 (2014). Hypoglossal-Facial Nerve Reconstruction Using a Y-Tube-Conduit Reduces Aberrant Synkinetic Movements of the Orbicularis Oculi and Vibrissal Muscles in Rats. Biomed Res. Int., 2014. LONDON: HINDAWI LTD. ISSN 2314-6141

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Abstract

The facial nerve is the most frequently damaged nerve in head and neck trauma. Patients undergoing facial nerve reconstruction often complain about disturbing abnormal synkinetic movements of the facial muscles (mass movements, synkinesis) which are thought to result from misguided collateral branching of regenerating motor axons and reinnervation of inappropriate muscles. Here, we examinedwhether use of an aorta Y-tube conduit during reconstructive surgery after facial nerve injury reduces synkinesis of orbicularis oris (blink reflex) and vibrissal (whisking) musculature. The abdominal aorta plus its bifurcation was harvested (N = 12) for Y-tube conduits. Animal groups comprised intact animals (Group 1), those receiving hypoglossal-facial nerve end-to-end coaptation alone (HFA; Group 2), and those receiving hypoglossal-facial nerve reconstruction using a Y-tube (HFA-Y-tube, Group 3). Videotape motion analysis at 4 months showed that HFA-Y-tube group showed a reduced synkinesis of eyelid and whisker movements compared to HFA alone.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Kaya, Yasemin UNSPECIFIED UNSPECIFIED UNSPECIFIED Ozsoy, Umut UNSPECIFIED UNSPECIFIED UNSPECIFIED Turhan, Murat UNSPECIFIED orcid.org/0000-0001-6140-1666 UNSPECIFIED Angelov, Doychin N. UNSPECIFIED UNSPECIFIED UNSPECIFIED Sarikcioglu, Levent UNSPECIFIED orcid.org/0000-0002-0825-6225 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-449108
DOI:	10.1155/2014/543020
Journal or Publication Title:	Biomed Res. Int.
Volume:	2014
Date:	2014
Publisher:	HINDAWI LTD
Place of Publication:	LONDON
ISSN:	2314-6141
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language MANUAL STIMULATION; IMPROVES RECOVERY; EYE-RETRACTION; REGENERATION; ANASTOMOSIS; WHISKING; LESION; INJURY; REINNERVATION; MOTONEURONS Multiple languages Biotechnology & Applied Microbiology; Medicine, Research & Experimental Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/44910