Universität zu Köln

Zyriax, B. -C., Letsch, B., Stock, S. and Windler, E. (2014). DELIGHT (Delay of impaired glucose tolerance by a healthy lifestyle trial) - A Feasibility Study on Implementing a Program of Sustainable Diabetes Prevention in German Companies. Exp. Clin. Endocrinol. Diabet., 122 (1). S. 20 - 27. STUTTGART: JOHANN AMBROSIUS BARTH VERLAG MEDIZINVERLAGE HEIDELBERG GMBH. ISSN 1439-3646

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Abstract

Background: Ca. 50% of Germans develop prediabetes in their lifetime. Though diabetes type 2 has been proven preventable, no screening for prediabetes has been implemented. DELIGHT was designed to assess if screening for individuals at risk and long-standing diabetes prevention is feasible in the setting of companies within the scope of the German legal health system. Materials and Methods: In 5 companies employees with a waist circumference of >= 94 (men) and >= 80 cm (women) were offered a checkup. Those with fasting plasma glucose >= 100 mg/dl (IFG) or >= 140 mg/dl 2 h after oral glucose load (IGT) were followed for 3 years with an optional moderate lifestyle program during the first year and quarterly assistance for another 2 years. Results: In 241 of 300 participants the self-measured waist circumference was confirmed as elevated. 3% had type 2 diabetes, while 37% had IFG (isolated in 96%) or IGT, of whom 91.4% (men) and 76.1% (women) had a metabolic syndrome. Within 3 years in those who had lost >= 1 kg, weight was reduced by 3.9 kg, risk factors were improved, and no case of diabetes had developed, while among those with weight loss of < 1 kg or weight gain, 10% of men and 5% of women had developed diabetes type 2. Screening for prediabetes did not increase the number or costs of drug prescriptions. Conclusions: Companies provide a suitable setting for screening for prediabetes. Long-term diabetes prevention is successfully feasible within the narrow financial frame of a legal insurance system without rise of costs.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Zyriax, B. -C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Letsch, B. UNSPECIFIED UNSPECIFIED UNSPECIFIED Stock, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Windler, E. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-450511
DOI:	10.1055/s-0033-1355423
Journal or Publication Title:	Exp. Clin. Endocrinol. Diabet.
Volume:	122
Number:	1
Page Range:	S. 20 - 27
Date:	2014
Publisher:	JOHANN AMBROSIUS BARTH VERLAG MEDIZINVERLAGE HEIDELBERG GMBH
Place of Publication:	STUTTGART
ISSN:	1439-3646
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language BODY-MASS INDEX; PHYSICAL-ACTIVITY; FOLLOW-UP; SOUTHERN GERMANY; FASTING GLUCOSE; WEIGHT-LOSS; RISK; PREVALENCE; MELLITUS; INDIVIDUALS Multiple languages Endocrinology & Metabolism Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/45051