Universität zu Köln

Tietze, Alesia A., Bordusa, Frank, Giernoth, Ralf ORCID: 0000-0003-2282-6586, Imhof, Diana ORCID: 0000-0003-4163-7334, Lenzer, Thomas, Maass, Astrid, Mrestani-Klaus, Carmen, Neundorf, Ines ORCID: 0000-0001-6450-3991, Oum, Kawon, Reith, Dirk ORCID: 0000-0003-1480-6745 and Stark, Annegret ORCID: 0000-0001-9547-3422 (2013). On the Nature of Interactions between Ionic Liquids and Small Amino-Acid-Based Biomolecules. ChemPhysChem, 14 (18). S. 4044 - 4065. WEINHEIM: WILEY-V C H VERLAG GMBH. ISSN 1439-7641

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Abstract

During the last decade, ionic liquids (ILs) have revealed promising properties and applications in many research fields, including biotechnology and biological sciences. The focus of this contribution is to give a critical review of the phenomena observed and current knowledge of the interactions occurring on a molecular basis. As opposed to the huge advances made in understanding the properties of proteins in ILs, complementary investigations dealing with interactions between ILs and peptides or oligopeptides are underrepresented and are mostly only of phenomenological nature. However, the field has received more attention in the last few years. This Review features a meta-analysis of the available data and findings and should, therefore, provide a basis for a scientifically profound understanding of the nature and mechanisms of interactions between ILs and structured or nonstructured peptides. Fundamental aspects of the interactions between different peptides/oligopeptides and ILs are complemented by sections on the experimental (spectroscopy, structural biology) and theoretical (computational chemistry) possibilities to explain the phenomena reported so far in the literature. In effect, this should lead to the development of novel applications and support the understanding of IL-solute interactions in general.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Tietze, Alesia A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Bordusa, Frank UNSPECIFIED UNSPECIFIED UNSPECIFIED Giernoth, Ralf UNSPECIFIED orcid.org/0000-0003-2282-6586 UNSPECIFIED Imhof, Diana UNSPECIFIED orcid.org/0000-0003-4163-7334 UNSPECIFIED Lenzer, Thomas UNSPECIFIED UNSPECIFIED UNSPECIFIED Maass, Astrid UNSPECIFIED UNSPECIFIED UNSPECIFIED Mrestani-Klaus, Carmen UNSPECIFIED UNSPECIFIED UNSPECIFIED Neundorf, Ines UNSPECIFIED orcid.org/0000-0001-6450-3991 UNSPECIFIED Oum, Kawon UNSPECIFIED UNSPECIFIED UNSPECIFIED Reith, Dirk UNSPECIFIED orcid.org/0000-0003-1480-6745 UNSPECIFIED Stark, Annegret UNSPECIFIED orcid.org/0000-0001-9547-3422 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-470035
DOI:	10.1002/cphc.201300736
Journal or Publication Title:	ChemPhysChem
Volume:	14
Number:	18
Page Range:	S. 4044 - 4065
Date:	2013
Publisher:	WILEY-V C H VERLAG GMBH
Place of Publication:	WEINHEIM
ISSN:	1439-7641
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language MOLECULAR-FORCE FIELD; PROTEIN AGGREGATION; PEPTIDE-SYNTHESIS; CONFORMATIONAL STABILITY; HOFMEISTER SERIES; ENZYME-ACTIVITY; PROTON-TRANSFER; DYNAMICS; SIMULATION; IMIDAZOLIUM Multiple languages Chemistry, Physical; Physics, Atomic, Molecular & Chemical Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/47003