Universität zu Köln

Held, Uwe, Rohner, Dennis and Rothamel, Daniel (2013). Early loading of hydrophilic titanium implants inserted in low-mineralized (D3 and D4) bone: one year results of a prospective clinical trial. Head Face Med., 9. LONDON: BMC. ISSN 1746-160X

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Abstract

Introduction: Pure titanium is the material of choice for contemporary dental implants. However, superficial reaction of the moderately rough titanium surface with atmospheric components decreases its hydrophilicity. INICELL (R) represents a chemical alteration and hydrophilization of a moderately rough i.e. sand-blasted and acid-etched titanium surface. The hydrophilicity leads to a more homogenous adsorption of proteins on the implant surface in-vitro, supporting the activation of a higher number of platelets and the generation of a homogenous, complete fibrin matrix in the early phases of osseointegration. This in turn helps to reduce the healing time and enhances the predictability of osseointegration in compromised bony situations. The objective of this case series trial was therefore to investigate if early loading (after 8 weeks) of hydrophilic INICELL implants is feasible in patients with reduced bone quality. Methods: In 10 patients, 35 hydrophilic implants were placed in sites revealing bone quality class 3 and 4, and uncovered after 4 weeks. Eight weeks later implants were released for loading if the tactile resistance was >= 35 Ncm. Lower resistances resulted in 12 weeks initial healing period. Insertion torque, ISQ, tactile resistance and vertical bone level were evaluated at implant installation, after 4 weeks (uncovering), 8 or 12 weeks (loading), and 12 weeks and one year after loading. Results: Mean implant insertion torque was 21 Ncm. 31 (88.6%) showed a tactile resistance of > 35 Ncm after eight weeks and were released for prosthetic loading. Eight weeks after insertion, one implant (2.9%) had to be removed following a soft tissue complication. One implant had to be removed after 4 weeks due to a technical complication (fractured Osstell-abutment), it was therefore excluded from the analysis. 33 of 34 implants (97%) were loaded to occlusion and were in situ/functional one year after implantation. ISQs increased from 43 at baseline to 63 at eight weeks, and 72 at three months after loading. Then, ISQ remained constant until one year after loading. Conclusions: Within the limitations of this prospective case series, hydrophilic implants may allow for shortening of the initial healing period even in bone with compromised density.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Held, Uwe UNSPECIFIED UNSPECIFIED UNSPECIFIED Rohner, Dennis UNSPECIFIED UNSPECIFIED UNSPECIFIED Rothamel, Daniel UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-470226
DOI:	10.1186/1746-160X-9-37
Journal or Publication Title:	Head Face Med.
Volume:	9
Date:	2013
Publisher:	BMC
Place of Publication:	LONDON
ISSN:	1746-160X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language RESONANCE FREQUENCY-ANALYSIS; EDENTULOUS MAXILLA; MODIFIED SURFACE; STABILITY; IMMEDIATE; ENERGY; APPOSITION; MECHANISMS; PLACEMENT; TOOTH Multiple languages Dentistry, Oral Surgery & Medicine Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/47022