Universität zu Köln

Tacke, Daniela, Koehler, Philipp ORCID: 0000-0002-7386-7495 and Cornely, Oliver A. (2013). Fungal endocarditis. Curr. Opin. Infect. Dis., 26 (6). S. 501 - 508. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1473-6527

Full text not available from this repository.

Abstract

Purpose of reviewFungal endocarditis remains a rare disease occurring mostly in patients with predisposing host conditions. Regarding its poor prognosis because of severe complications, there is an urgent need for properly established treatment guidelines and prophylaxis for patients at risk. In this review we provide up-to-date information on treatment recommendations, and discuss recent case reports on fungal endocarditis and challenges in prophylaxis and treatment.Recent findingsOver the last year, an increase in cases caused by non-albicans species of Candida and other fungi like Fusarium solani, Lodderomyces elongisporus and Exophiala dermatitidis was reported. They were treated individually in case-by-case approaches, lacking randomized controlled trials and, mostly, treatment recommendations.SummaryThe scarcity of fungal endocarditis demands a high index of suspicion and knowledge of the group of at-risk patients. Diagnosis aggressively pursued by echocardiography and multiple blood cultures or surgical specimens has the potential to improve outcome. Candida endocarditis should be treated immediately, including surgical treatment in combination with liposomal amphotericin B or caspofungin with optional addition of flucytosine. Aspergillus endocarditis requires rapid surgery and voriconazole.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Tacke, Daniela UNSPECIFIED UNSPECIFIED UNSPECIFIED Koehler, Philipp UNSPECIFIED orcid.org/0000-0002-7386-7495 UNSPECIFIED Cornely, Oliver A. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-471234
DOI:	10.1097/QCO.0000000000000009
Journal or Publication Title:	Curr. Opin. Infect. Dis.
Volume:	26
Number:	6
Page Range:	S. 501 - 508
Date:	2013
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Place of Publication:	PHILADELPHIA
ISSN:	1473-6527
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CANDIDA-PARAPSILOSIS ENDOCARDITIS; INFECTIVE ENDOCARDITIS; ASPERGILLUS-ENDOCARDITIS; AORTIC-VALVE; DIAGNOSIS; GUIDELINES; SOCIETY Multiple languages Infectious Diseases Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/47123