Universität zu Köln

Hoelscher, A. H. and Fetzner, U. K. (2012). Carcinoma of the esophagus, esophagogastric junction, and stomach. Cooperation between pathology and surgery. Pathologe, 33. S. 246 - 253. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-1963

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Abstract

Cooperation between pathology and surgery plays a decisive role in the treatment of carcinoma of the esophagus, esophagogastric junction, and stomach. Preoperatively, the carcinoma is confirmed and the histologic type, grading, type of extension (stomach) and immunohistochemical or molecular-biological parameters, if necessary, are determined. For exclusion or diagnosis of distant metastases, peritoneal carcinosis, or secondary tumors, further biopsies or cytological examinations may be required. All results contribute to the individualized treatment. In case of endoscopic treatment, the completeness of resection of the carcinoma and the depth of infiltration must be identified with extraordinary diligence. Postoperative proof of tumor, location, histological type, completeness of resection and safety margin have to be identified. Detailed T-status, N-status with declaration of the ratio of affected and nonaffected number of lymph nodes, location of affected lymph nodes, extracapsular lymph node spread, invasion of lymphatic and vascular vessels and perineural sheets are important parameters. The description of tumor regression after neoadjuvant treatment (histomorphological response) is of special interest.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Hoelscher, A. H. UNSPECIFIED UNSPECIFIED UNSPECIFIED Fetzner, U. K. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-479655
DOI:	10.1007/s00292-012-1680-y
Journal or Publication Title:	Pathologe
Volume:	33
Page Range:	S. 246 - 253
Date:	2012
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1432-1963
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language NEOADJUVANT RADIOCHEMOTHERAPY; CANCER; ESOPHAGECTOMY; MUCOSAL; REGRESSION; NUMBER; IMPACT Multiple languages Pathology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/47965