Universität zu Köln

Cieslik, Edna C., Zilles, Karl ORCID: 0000-0001-9296-9959, Grefkes, Christian ORCID: 0000-0002-1656-720X and Eickhoff, Simon B. ORCID: 0000-0001-6363-2759 (2011). Dynamic interactions in the fronto-parietal network during a manual stimulus-response compatibility task. Neuroimage, 58 (3). S. 860 - 870. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE. ISSN 1095-9572

Full text not available from this repository.

Abstract

Attentional orienting can be modulated by stimulus-driven bottom-up as well as task-dependent top-down processes. In a recent study we investigated the interaction of both processes in a manual stimulus response compatibility task. Whereas the intraparietal sulcus (IPS) and the dorsal premotor cortex (dPMC) were involved in orienting towards the stimulus side facilitating congruent motor responses, the right temporoparietal junction (TPJ) right dorsolateral prefrontal cortex (DLPFC) as well as the preSMA sustained top-down control processes involved in voluntary reorienting. Here we used dynamic causal modelling to investigate the contributions and task-dependent interactions between these regions. Thirty-six models were tested, all of which included bilateral IPS, dPMC and primary motor cortex (M1) as a network transforming visual input into motor output as well as the right TPJ, right DLPFC and the preSMA as task-dependent top-down regions influencing the coupling within the dorsal network. Our data showed the right temporoparietal junction to play a mediating role during attentional reorienting processes by modulating the inter-hemispheric balance between both IPS. Analysis of connection strength supported the proposed role of the preSMA in controlling motor responses promoting or suppressing activity in primary motor cortex. As the results did not show a clear tendency towards a role of the right DLPFC, we propose this region, against the usual interpretation of an inhibitory influence in stimulus response compatibility tasks, to subserve generic monitoring processes. Our DCM study hence provides evidence for context-dependent top-down control of right TPJ and DLPFC as well as the preSMA in stimulus response compatibility. (C) 2011 Elsevier Inc. All rights reserved.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Cieslik, Edna C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Zilles, Karl UNSPECIFIED orcid.org/0000-0001-9296-9959 UNSPECIFIED Grefkes, Christian UNSPECIFIED orcid.org/0000-0002-1656-720X UNSPECIFIED Eickhoff, Simon B. UNSPECIFIED orcid.org/0000-0001-6363-2759 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-488227
DOI:	10.1016/j.neuroimage.2011.05.089
Journal or Publication Title:	Neuroimage
Volume:	58
Number:	3
Page Range:	S. 860 - 870
Date:	2011
Publisher:	ACADEMIC PRESS INC ELSEVIER SCIENCE
Place of Publication:	SAN DIEGO
ISSN:	1095-9572
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ANTISACCADE EYE-MOVEMENTS; EFFECTIVE CONNECTIVITY; FRONTAL-CORTEX; NEURAL BASIS; MOTOR AREAS; INHIBITION; VOLUNTARY; ATTENTION; PARIETAL; HAND Multiple languages Neurosciences; Neuroimaging; Radiology, Nuclear Medicine & Medical Imaging Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/48822