Brisse, Herve J., McCarville, M. Beth, Granata, Claudio ORCID: 0000-0003-3072-4096, Krug, K. Barbara, Wootton-Gorges, Sandra L., Kanegawa, Kimio, Giammarile, Francesco, Schmidt, Matthias, Shulkin, Barry L., Matthay, Katherine K., Lewington, Valerie J., Sarnacki, Sabine ORCID: 0000-0003-4304-5578, Hero, Barbara, Kaneko, Michio, London, Wendy B., Pearson, Andrew D. J., Cohn, Susan L. and Monclair, Tom (2011). Guidelines for Imaging and Staging of Neuroblastic Tumors: Consensus Report from the International Neuroblastoma Risk Group Project. Radiology, 261 (1). S. 243 - 258. OAK BROOK: RADIOLOGICAL SOC NORTH AMERICA. ISSN 0033-8419

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Abstract

Neuroblastoma is an enigmatic disease entity; some tumors disappear spontaneously without any therapy, while others progress with a fatal outcome despite the implementation of maximal modern therapy. However, strong prognostic factors can accurately predict whether children have good or bad disease at diagnosis, and the clinical stage is currently the most significant and clinically relevant prognostic factor. Therefore, for an individual patient, proper staging is of paramount importance for risk assessment and selection of optimal treatment. In 2009, the International Neuroblastoma Risk Group (INRG) Project proposed a new staging system designed for tumor staging before any treatment, including surgery. Compared with the focus of the International Neuroblastoma Staging System, which is currently the most used, the focus has now shifted from surgicopathologic findings to imaging findings. The new INRG Staging System includes two stages of localized disease, which are dependent on whether image-defined risk factors (IDRFs) are or are not present. IDRFs are features detected with imaging at the time of diagnosis. The present consensus report was written by the INRG Imaging Committee to optimize imaging and staging and reduce interobserver variability. The rationales for using imaging methods (ultrasonography, magnetic resonance imaging, computed tomography, and scintigraphy), as well as technical guidelines, are described. Definitions of the terms recommended for assessing IDRFs are provided with examples. It is anticipated that the use of standardized nomenclature will contribute substantially to more uniform staging and thereby facilitate comparisons of clinical trials conducted in different parts of the world. (C) RSNA, 2011

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Brisse, Herve J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
McCarville, M. BethUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Granata, ClaudioUNSPECIFIEDorcid.org/0000-0003-3072-4096UNSPECIFIED
Krug, K. BarbaraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wootton-Gorges, Sandra L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kanegawa, KimioUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Giammarile, FrancescoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schmidt, MatthiasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Shulkin, Barry L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Matthay, Katherine K.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lewington, Valerie J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sarnacki, SabineUNSPECIFIEDorcid.org/0000-0003-4304-5578UNSPECIFIED
Hero, BarbaraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kaneko, MichioUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
London, Wendy B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pearson, Andrew D. J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cohn, Susan L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Monclair, TomUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-488612
DOI: 10.1148/radiol.11101352
Journal or Publication Title: Radiology
Volume: 261
Number: 1
Page Range: S. 243 - 258
Date: 2011
Publisher: RADIOLOGICAL SOC NORTH AMERICA
Place of Publication: OAK BROOK
ISSN: 0033-8419
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
WHOLE-BODY MRI; NERVOUS-SYSTEM METASTASES; MIBG-SCINTIGRAPHY; PEDIATRIC-PATIENTS; LOCAL-CONTROL; DIAGNOSIS; CHILDREN; INRG; CT; CRITERIAMultiple languages
Radiology, Nuclear Medicine & Medical ImagingMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/48861

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