Universität zu Köln

Buzard, Kurt, Zhang, Jue-Rong, Thumann, Gabriella, Stripecke, Renata and Sunalp, Murad (2010). Two cases of toxic anterior segment syndrome from generic trypan blue. J. Cataract. Refract. Surg., 36 (12). S. 2195 - 2200. NEW YORK: ELSEVIER SCIENCE INC. ISSN 0886-3350

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Abstract

We report 2 cases of toxic anterior segment syndrome (TASS) resulting from impurities in generic trypan blue that was administered intracamerally to improve visualization of the capsule. Histology of the corneal buttons revealed foci of inflammatory response and complete loss of endothelial cells. Cell culture analysis showed that the generic trypan blue was approximately twice as toxic to the endothelium as a proprietary trypan blue. Ophthalmologists should be aware that any substance administered intraocularly can be a source of complications, and they should know the source of all material used in surgery.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Buzard, Kurt UNSPECIFIED UNSPECIFIED UNSPECIFIED Zhang, Jue-Rong UNSPECIFIED UNSPECIFIED UNSPECIFIED Thumann, Gabriella UNSPECIFIED UNSPECIFIED UNSPECIFIED Stripecke, Renata UNSPECIFIED UNSPECIFIED UNSPECIFIED Sunalp, Murad UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-491617
DOI:	10.1016/j.jcrs.2010.09.017
Journal or Publication Title:	J. Cataract. Refract. Surg.
Volume:	36
Number:	12
Page Range:	S. 2195 - 2200
Date:	2010
Publisher:	ELSEVIER SCIENCE INC
Place of Publication:	NEW YORK
ISSN:	0886-3350
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ENDOTHELIAL-CELL DESTRUCTION; CATARACT-SURGERY; STERILE ENDOPHTHALMITIS; BENZALKONIUM CHLORIDE; INTRAOCULAR-LENS; CAPSULE; CAPSULORHEXIS; SECONDARY; MATURE Multiple languages Ophthalmology; Surgery Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/49161