Gerfer, Stephen ORCID: 0000-0002-6568-6766, Gaisendrees, Christopher ORCID: 0000-0002-7232-3330, Djordjevic, Ilija ORCID: 0000-0002-5810-8626, Ivanov, Borko ORCID: 0000-0001-8052-8232, Merkle, Julia, Eghbalzadeh, Kaveh, Schlachtenberger, Georg, Rustenbach, Christian, Sabashnikov, Anton, Kuhn-Regnier, Ferdinand, Mader, Navid and Wahlers, Thorsten . Gender-related propensity score match analysis of ECMO therapy in postcardiotomy cardiogenic shock in patients after myocardial revascularization. Perfusion-UK. LONDON: SAGE PUBLICATIONS LTD. ISSN 1477-111X

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Abstract

Background: Gender is known to influence the pathophysiology and pathogenesis of the coronary vascular disease. Data on gender-related differences in patients with veno-arterial extracorporeal membrane oxygenation due to postcardiotomy cardiogenic shock is lacking in current literature. We aimed to analyze the impact of gender on intraoperative and short-term outcomes of vaECMO patients after coronary surgery and postcardiotomy cardiogenic shock. Methods: Between 2006 and 2017, a total of 92 patients with PCS after CABG underwent vaECMO-implantation at our institution. After a 1:1 propensity score match (PSM) for relevant preoperative data, we identified a cohort of 32 patients, 16 males, and 16 females. Periprocedural and short-term outcome data were analyzed with respect to sex differences. Results: The mean age was 64 +/- 11 years, and 79% (n = 73) were male patients. Clinical outcomes showed a 30-day all-cause mortality of 64% (n = 59). After PSM, male patients showed a significantly smaller number of arterial grafts (0.4 +/- 0.53 male vs 1.1 +/- 0.7 female; p = 0.037). Thirty-day all-cause mortality did not differ between the groups (56% male vs 75% female; p = 0.262). In general, short-term outcome data were comparable without significant differences for the matched groups. Conclusion: Gender has no impact on patients with vaECMO therapy due to PCS in isolated coronary surgery.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Gerfer, StephenUNSPECIFIEDorcid.org/0000-0002-6568-6766UNSPECIFIED
Gaisendrees, ChristopherUNSPECIFIEDorcid.org/0000-0002-7232-3330UNSPECIFIED
Djordjevic, IlijaUNSPECIFIEDorcid.org/0000-0002-5810-8626UNSPECIFIED
Ivanov, BorkoUNSPECIFIEDorcid.org/0000-0001-8052-8232UNSPECIFIED
Merkle, JuliaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Eghbalzadeh, KavehUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schlachtenberger, GeorgUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rustenbach, ChristianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sabashnikov, AntonUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kuhn-Regnier, FerdinandUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mader, NavidUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wahlers, ThorstenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-565706
DOI: 10.1177/02676591211004363
Journal or Publication Title: Perfusion-UK
Publisher: SAGE PUBLICATIONS LTD
Place of Publication: LONDON
ISSN: 1477-111X
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
Cardiac & Cardiovascular Systems; Peripheral Vascular DiseaseMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/56570

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