Universität zu Köln

Luengas-Wuerzinger, Veronica, Rawert, Friederike, Spee, Sabrina Classen-Von, Baransi, Saher, Schuler, Esther, Carrizo, Katharina, Mallmann, Peter and Lampe, Bjoern (2021). Role of the Cardiophrenic Lymph Node Status After Neoadjuvant Chemotherapy in Primary Advanced Ovarian Cancer. Anticancer Res., 41 (10). S. 5025 - 5032. ATHENS: INT INST ANTICANCER RESEARCH. ISSN 1791-7530

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Abstract

Background/Aim: This study investigated the cardiophrenic lymph node (CPLN) status before and after neoadjuvant chemotherapy (NACT), as its presence seems to have a rather prognostic significance in patients with advanced ovarian cancer. Patients and Methods: The baseline computed tomography scans of 66 patients with advanced ovarian cancer primary treated with NACT between March 2015 and June 2020 were reviewed. A CPLN enlargement was defined as =5 mm. Results: 44% (n=29) of the patients had enlarged CPLNs; 10.7% (n=3) showed a complete response, 71.4% (n=20) a partial response, and 17.9% ( n=5) a stable disease after NACT. There was no significant difference between the response to NACT measured according to the status of CPLN compared to other biomarkers in the CPLN group. Conclusion: Patients with CPLN enlargement have a tendency to an impaired prognosis. The response of CPLN to NACT was comparable to the response of established biomarkers, adding a monitoring function to the CPLN.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Luengas-Wuerzinger, Veronica UNSPECIFIED UNSPECIFIED UNSPECIFIED Rawert, Friederike UNSPECIFIED UNSPECIFIED UNSPECIFIED Spee, Sabrina Classen-Von UNSPECIFIED UNSPECIFIED UNSPECIFIED Baransi, Saher UNSPECIFIED UNSPECIFIED UNSPECIFIED Schuler, Esther UNSPECIFIED UNSPECIFIED UNSPECIFIED Carrizo, Katharina UNSPECIFIED UNSPECIFIED UNSPECIFIED Mallmann, Peter UNSPECIFIED UNSPECIFIED UNSPECIFIED Lampe, Bjoern UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-569464
DOI:	10.21873/anticanres.15317
Journal or Publication Title:	Anticancer Res.
Volume:	41
Number:	10
Page Range:	S. 5025 - 5032
Date:	2021
Publisher:	INT INST ANTICANCER RESEARCH
Place of Publication:	ATHENS
ISSN:	1791-7530
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language PROGNOSTIC-SIGNIFICANCE; PRIMARY SURGERY; FEASIBILITY; DISSECTION; TRIAL Multiple languages Oncology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/56946