Universität zu Köln

Tuschen, Katharina, Anders, Johanna, Elfanish, Amin, Schildgen, Verena, Schildgen, Oliver ORCID: 0000-0003-4297-9627, Becker, Jan Ulrich and Weidemann, Alexander ORCID: 0000-0002-7984-9597 (2021). Renal transplantation after recovery from COVID-19-a case report with implications for transplant programs in the face of the ongoing corona-pandemic. BMC Nephrol., 22 (1). LONDON: BMC. ISSN 1471-2369

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Abstract

Background The ongoing coronavirus pandemic has major impacts on both patients and healthcare systems worldwide, thus creating new realities. Patients on maintenance dialysis listed for renal transplantation are a vulnerable subgroup with many comorbidities and recurring contacts with the healthcare system. Due to the COVID-19 pandemic transplant numbers have dropped considerably, further increasing waiting times in this high-risk population. On the other hand, knowledge of the severity of SARS-CoV-2 infection in immunocompromised patients, development and persistence of neutralising antibodies in such patients is just emerging. It is unclear how best to address the dilemma of postponing the life-saving transplantation. Case presentation We present a case report of a successful kidney transplantation only 65 days after the recipient was hospitalized for treatment of COVID-19 pneumonia. In a follow up of 9 months, we observed no signs of recurrent disease and transplant function is excellent. Monitoring SARS-CoV-2 antibody response demonstrates stable IgG levels. Conclusion This reassuring case provides guidance to transplant centers how to proceed with kidney transplantation safely during the pandemic. Careful consideration of risks and benefits of the organ offer, full recovery from COVID-19 symptoms and the presence of a positive SARS-CoV-2 IgG antibody test, qualifies for kidney transplantation.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Tuschen, Katharina UNSPECIFIED UNSPECIFIED UNSPECIFIED Anders, Johanna UNSPECIFIED UNSPECIFIED UNSPECIFIED Elfanish, Amin UNSPECIFIED UNSPECIFIED UNSPECIFIED Schildgen, Verena UNSPECIFIED UNSPECIFIED UNSPECIFIED Schildgen, Oliver UNSPECIFIED orcid.org/0000-0003-4297-9627 UNSPECIFIED Becker, Jan Ulrich UNSPECIFIED UNSPECIFIED UNSPECIFIED Weidemann, Alexander UNSPECIFIED orcid.org/0000-0002-7984-9597 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-573510
DOI:	10.1186/s12882-021-02448-1
Journal or Publication Title:	BMC Nephrol.
Volume:	22
Number:	1
Date:	2021
Publisher:	BMC
Place of Publication:	LONDON
ISSN:	1471-2369
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language Urology & Nephrology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/57351