Roheger, Mandy ORCID: 0000-0002-6015-3194, Kalbe, Elke, Corbett, Anne ORCID: 0000-0003-2015-0316, Brooker, Helen ORCID: 0000-0002-7908-263X and Ballard, Clive (2021). Predictors of activities of daily living in heathy older adults: Who benefits most from online cognitive training? Brain Behav., 11 (11). HOBOKEN: WILEY. ISSN 2162-3279

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Abstract

Objectives To investigate the course of activities of daily living (IADL) functioning and possible predictors of performance changes in healthy older adults conducting either a General Cognitive Training (GCT) or a Reasoning Cognitive Training (ReaCT) or no training (control group, CG) over a period of 6 weeks, 3 months, and 6 months. Setting and participants An online, home-based GCT and ReaCT including n = 2913 healthy participants (GCT: n = 1096; ReaCT: n = 1022; CG: n = 794) aged 60 years and older. Methods Multilevel analysis were calculated to explore the nature of our outcome variables of IADL part A (independence) and part B (difficulty of tasks), and to detect possible predictors for participants' performance on IADL after CT. Results The random slopes models fitted better for the outcomes IADL Part B in the GCT group (chi(2)(2) = 18.78, p < .01), and both IADL Part A and Part B in the ReaCT group (chi(2)(2) = 28.57, p < .01; chi(2)(2) = 63.38, p < .01, respectively), indicating different changes over time for individual participants. Female sex was a significant predictor of IADL change in the ReaCT group, showing that females benefited most in both IADL scores (IADL A: 0.01, p < .01; IADL B: 0.004, p < .01). No other significant predictors for IADL changes were identified. Conclusion and implication The particular effectiveness in women is of clinical relevance, as IADL is typically more impaired in women than in men in advanced age. Following a personalized medicine approach, identifying predictors of non-pharmacological intervention success is of utmost importance.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Roheger, MandyUNSPECIFIEDorcid.org/0000-0002-6015-3194UNSPECIFIED
Kalbe, ElkeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Corbett, AnneUNSPECIFIEDorcid.org/0000-0003-2015-0316UNSPECIFIED
Brooker, HelenUNSPECIFIEDorcid.org/0000-0002-7908-263XUNSPECIFIED
Ballard, CliveUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-585295
DOI: 10.1002/brb3.2388
Journal or Publication Title: Brain Behav.
Volume: 11
Number: 11
Date: 2021
Publisher: WILEY
Place of Publication: HOBOKEN
ISSN: 2162-3279
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
INSTRUMENTAL ACTIVITIES; FUNCTIONAL STATUS; PEOPLE; LIMITATIONS; DISABILITY; BRAINMultiple languages
Behavioral Sciences; NeurosciencesMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/58529

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