Universität zu Köln

Baessler, K., Windemut, S., Chiantera, V, Koehler, C. and Sehouli, J. (2021). Sexual, bladder and bowel function following different minimally invasive techniques of radical hysterectomy in patients with early-stage cervical cancer. Clin. Transl. Oncol., 23 (11). S. 2335 - 2344. CHAM: SPRINGER INT PUBL AG. ISSN 1699-3055

Full text not available from this repository.

Abstract

Purpose Despite the establishment of radical surgery for therapy of cervical cancer, data on quality of life and patient-reported outcomes are scarce. The aim of this retrospective cohort study was to evaluate bladder, bowel and sexual function in women who underwent minimally invasive surgery for early-stage cervical cancer. Methods From 2007-2013, 261 women underwent laparoscopically assisted radical vaginal hysterectomy (LARVH = 45), vaginally assisted laparoscopic or robotic radical hysterectomy (VALRRH = 61) or laparoscopic total mesometrial resection (TMMR = 25) and 131 of them completed the validated German version of the Australian Pelvic Floor Questionnaire (PFQ). Results were compared with controls recruited from gynecological clinics (n = 24) and with urogynecological patients (n = 63). Results Groups were similar regarding age, BMI and parity. The TMMR group had significantly shorter median follow-up (16 months versus 70 and 36 months). Postoperatively, deterioration of bladder function was reported by 70%, 57% and 44% in the LARVH, VARRVH and TMMR groups, respectively (p = 0.734). Bowel function was significantly worse after TMMR with a higher deterioration rate in 72 versus 43% (LARVH) and 47% (VARRVH) with a correspondingly higher bowel dysfunction score of 2.9 versus 1.5 and 1.8, respectively and 1.8 in urogynaecological patients. Sexual dysfunction was common in all surgical groups. 38% considered their vagina too short which was significantly associated with deep dyspareunia. Compared with controls, surgical groups had significantly increased PFQ scores. Conclusion Pelvic floor dysfunction commonly deteriorates and negatively impacts on quality of life after minimally invasive radical hysterectomy, especially bowel function after TMMR. Pelvic floor symptoms should routinely be addressed pre- and postoperatively.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Baessler, K. UNSPECIFIED UNSPECIFIED UNSPECIFIED Windemut, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Chiantera, V UNSPECIFIED UNSPECIFIED UNSPECIFIED Koehler, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Sehouli, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-592391
DOI:	10.1007/s12094-021-02632-7
Journal or Publication Title:	Clin. Transl. Oncol.
Volume:	23
Number:	11
Page Range:	S. 2335 - 2344
Date:	2021
Publisher:	SPRINGER INT PUBL AG
Place of Publication:	CHAM
ISSN:	1699-3055
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language TOTAL MESOMETRIAL RESECTION; QUALITY-OF-LIFE; PELVIC FLOOR QUESTIONNAIRE; WOMEN; VALIDATION; DYSFUNCTION; SURVIVAL; OUTCOMES Multiple languages Oncology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/59239