Universität zu Köln

Pilkington, Patrick, Lopci, Egesta ORCID: 0000-0001-9732-1094, Adam, Judit A., Kobe, Carsten, Goffin, Karolien and Herrmann, Ken (2021). FDG-PET/CT Variants and Pitfalls in Haematological Malignancies. Semin. Nucl. Med., 51 (6). S. 554 - 572. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC. ISSN 1558-4623

Full text not available from this repository.

Abstract

Hematologic malignancies represent a vast group of hematopoietic and lymphoid cancers that typically involve the blood, the bone marrow, and the lymphatic organs. Due to extensive research and well defined and standardized response criteria, the role of [F-18]FDGPET/CT is well defined in these malignancies. Never the less, the reliability of visual and quantitative interpretation of PET/CT may be impaired by several factors including inconsistent scanning protocols and image reconstruction methods. Furthermore, the uptake of [F-18]FDG not only reflects tissue glucose consumption by malignant lesions, but also in other situations such as in inflammatory lesions, local and systemic infections, benign tumors, reactive thymic hyperplasia, histiocytic infiltration, among others; or following granulocyte colony stimulating factors therapy, radiation therapy, chemotherapy or surgical interventions, all of which are a potential source of false-positive or negative interpretations. Therefore it is of paramount importance for the Nuclear Medicine Physician to be familiar with, not only the normal distribution of [F-18]FDG in the body, but also with the most frequent findings that may hamper a correct interpretation of the scan, which could ultimately alter the patients management. In this review, we describe these myriad of situations so the interpreting physician can be familiar with them, providing tools for their correct identification and interpretation when possible. (C) 2021 Elsevier Inc. All rights reserved.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Pilkington, Patrick UNSPECIFIED UNSPECIFIED UNSPECIFIED Lopci, Egesta UNSPECIFIED orcid.org/0000-0001-9732-1094 UNSPECIFIED Adam, Judit A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Kobe, Carsten UNSPECIFIED UNSPECIFIED UNSPECIFIED Goffin, Karolien UNSPECIFIED UNSPECIFIED UNSPECIFIED Herrmann, Ken UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-597580
DOI:	10.1053/j.semnuclmed.2021.06.014
Journal or Publication Title:	Semin. Nucl. Med.
Volume:	51
Number:	6
Page Range:	S. 554 - 572
Date:	2021
Publisher:	W B SAUNDERS CO-ELSEVIER INC
Place of Publication:	PHILADELPHIA
ISSN:	1558-4623
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language NON-HODGKINS-LYMPHOMA; CLINICAL-PRACTICE GUIDELINES; BONE-MARROW INVOLVEMENT; B-CELL LYMPHOMA; HEALTH-ORGANIZATION CLASSIFICATION; ACUTE MYELOID-LEUKEMIA; MULTIPLE-MYELOMA; F-18-FDG PET/CT; RESPONSE ASSESSMENT; ATTENUATION CORRECTION Multiple languages Radiology, Nuclear Medicine & Medical Imaging Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/59758