Haas, Mark, Mirocha, James, Amann, Kerstin, Bajema, Ingeborg M., Barisoni, Laura, Becker, Jan Ulrich, Jennette, J. Charles, Joh, Kenuske, Ljubanovic, Danica Galesic, Roberts, Ian S. D., Roelofs, Joris J., Sethi, Sanjeev, Suarez, Raul, Zeng, Caihong and Seshan, Surya, V (2022). Impact of Consensus Definitions on Identification of Glomerular Lesions by Light and Electron Microscopy. Kidney Int. Rep., 7 (1). S. 78 - 87. NEW YORK: ELSEVIER SCIENCE INC. ISSN 2468-0249

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Abstract

Introduction: In 2020, a working group of 13 renal pathologists published consensus definitions for 47 individual glomerular lesions found on light microscopy (LM) and 47 glomerular lesions and 9 normal structures found on electron microscopy (EM). Methods: To test the impact of these definitions on identification of these lesions and structures, 2 surveys were circulated to all members of the Renal Pathology Society (RPS), each having 32 images (19 LM, 13 EM) and accompanying questions with 5 multiple-choice answers, one being the consensus choice of the working group. The first survey (survey 1 [S1]), answered by 297 RPS members, was sent in September 2020, before publication of the consensus definitions. The second (survey 2 (S2]), with images of the same lesions and structures (but not the same images) and the same questions and multiple choices in different order, was sent in April 2020, 5 months after the publication of the definitions. Results: S2 was taken by 181 RPS members; 64% also took 51 and 61% reported having read the definitions paper (def. paper). Mean agreement with the consensus answers increased modestly between the 2 surveys (65.2% vs. 72.0%, P = 0.097); the increase was greater and significant when only respondents to S2 who read the def. paper were considered (65.2% vs. 74.8%, P = 0.026). Furthermore, in S2 agreement with consensus answers was greater among respondents who read this paper versus those who did not (66.9% vs. 74.8%, P < 0.0001). Conclusions: Publication of the consensus definitions modestly improved interobserver agreement in identification of glomerular lesions.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Haas, MarkUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mirocha, JamesUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Amann, KerstinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bajema, Ingeborg M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Barisoni, LauraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Becker, Jan UlrichUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jennette, J. CharlesUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Joh, KenuskeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ljubanovic, Danica GalesicUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Roberts, Ian S. D.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Roelofs, Joris J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sethi, SanjeevUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Suarez, RaulUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Zeng, CaihongUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Seshan, Surya, VUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-603347
DOI: 10.1016/j.ekir.2021.10.014
Journal or Publication Title: Kidney Int. Rep.
Volume: 7
Number: 1
Page Range: S. 78 - 87
Date: 2022
Publisher: ELSEVIER SCIENCE INC
Place of Publication: NEW YORK
ISSN: 2468-0249
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
OXFORD CLASSIFICATION; IGA NEPHROPATHY; LUPUS NEPHRITIS; PATHOLOGICAL CLASSIFICATION; OF-HEALTH; REPRODUCIBILITY; SOCIETYMultiple languages
Urology & NephrologyMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/60334

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