Universität zu Köln

Lentzen, Max-Philipp, Riekert, Maximilian, Zirk, Matthias, Nickenig, Hans-Joachim, Zoller, Joachim E. and Kreppel, Matthias (2022). A Volumetric and Morphological Analysis of Recurrent Odontogenic Keratocysts by Semiautomatic Segmentation. J. Craniofac. Surg., 33 (3). S. E294 - 5. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1536-3732

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Abstract

Purpose: The authors conducted this study to provide morphological and volumetric data of recurrent odontogenic keratocysts of the upper and lower jaw to emphasize risk factors in accordance with their radiological appearance and guide clinical decisions for jeopardized patients. Methods: By applying the open-source software ITK-Snap on cone-beam computed tomography images, volumetric measurements of histopathologically diagnosed recurrent odontogenic keratocysts could be performed. For statistical investigations, descriptive statistics and independent Student t test were performed. The intraclass correlation coefficient was used to assess intra- and inter-rater reliabilities. P values P < 0.05 were considered significant. Results: Forty patients (24 male and 16 female) were included in this study. Recurrent odontogenic keratocysts had a mean maximum diameter of 28.91 mm +/- 12.00 mm and a mean volume of 4.48 cm(3) +/- 4.29 cm(3). According to morphology, irregular shape (P = 0.001; P = 0.005), unclear margin (P = 0.001; P = 0.001), multilocular morphology (P = 0.001; P = 0.001), and cortical bone exceedance (P = 0.001; P = 0.007) are statistically significantly associated with a larger cyst diameter and volume. Furthermore, significant differences by diameter and volume could be shown between patients with and without iliac crest graft reconstruction (P = 0.001; P = 0.001). Conclusions: Volumetric analysis reveals that recurrent odontogenic keratocysts show large diametric and volumetric extension that leads to complex reconstruction by iliac crest grafts, adding an argument that special attention should be paid to this entity and its recurrence. in case of difficult histopathological examination, lesions with irregular shape and margin, multilocular morphology, cortical bone exceedance, and clinically visible symptoms should be considered for close morphological and volumetric clinico- radiological follow-up.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Lentzen, Max-Philipp UNSPECIFIED UNSPECIFIED UNSPECIFIED Riekert, Maximilian UNSPECIFIED UNSPECIFIED UNSPECIFIED Zirk, Matthias UNSPECIFIED UNSPECIFIED UNSPECIFIED Nickenig, Hans-Joachim UNSPECIFIED UNSPECIFIED UNSPECIFIED Zoller, Joachim E. UNSPECIFIED UNSPECIFIED UNSPECIFIED Kreppel, Matthias UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-657813
DOI:	10.1097/SCS.0000000000008161
Journal or Publication Title:	J. Craniofac. Surg.
Volume:	33
Number:	3
Page Range:	S. E294 - 5
Date:	2022
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Place of Publication:	PHILADELPHIA
ISSN:	1536-3732
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language RECONSTRUCTION Multiple languages Surgery Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/65781