Universität zu Köln

Goertz, Lukas, Borggrefe, Jan ORCID: 0000-0003-2908-7560, Abdullayev, Nuran ORCID: 0000-0003-4522-537X, Celik, Erkan ORCID: 0000-0001-5687-7707, Pennig, Lenhard, Timmer, Marco, Luers, Jan-Christoffer, Schlamann, Marc and Kabbasch, Christoph . Initial clinical experience with N-hexyl cyanoacrylate for neuroendovascular embolization. Interv. Neuroradiol.. THOUSAND OAKS: SAGE PUBLICATIONS INC. ISSN 2385-2011

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Abstract

Objective To report our initial clinical experience with N-hexyl cyanoacrylate (NHCA), a novel liquid agent for neurovascular embolization. Methods Four paragangliomas were treated with percutaneous embolization using NHCA as the sole embolic material. In one dural arteriovenous fistula (dAVF), NHCA was used in combination with other embolic materials. Procedural specifics, complications and angiographic results were retrospectively evaluated. Results Total or subtotal devascularization was obtained in 3 of the 4 paragangliomas. In the largest tumor, only partial devascularization could be achieved. The dAVF was completely occluded. Catheter entrapment did not occur. After dAVF treatment, the patient had an asymptomatic lacunar infarction, while there was no procedural morbidity related to paraganglioma treatment. Conclusions In this series, neurovascular embolization with NHCA was feasible and effective. It may be particularly beneficial for small and tortuous vessels that require low-profile catheterization and a slow and controlled polymerization. Further studies are necessary to prove the benefits of NHCA over established embolic agents.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Goertz, Lukas UNSPECIFIED UNSPECIFIED UNSPECIFIED Borggrefe, Jan UNSPECIFIED orcid.org/0000-0003-2908-7560 UNSPECIFIED Abdullayev, Nuran UNSPECIFIED orcid.org/0000-0003-4522-537X UNSPECIFIED Celik, Erkan UNSPECIFIED orcid.org/0000-0001-5687-7707 UNSPECIFIED Pennig, Lenhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Timmer, Marco UNSPECIFIED UNSPECIFIED UNSPECIFIED Luers, Jan-Christoffer UNSPECIFIED UNSPECIFIED UNSPECIFIED Schlamann, Marc UNSPECIFIED UNSPECIFIED UNSPECIFIED Kabbasch, Christoph UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-664993
DOI:	10.1177/15910199221111288
Journal or Publication Title:	Interv. Neuroradiol.
Publisher:	SAGE PUBLICATIONS INC
Place of Publication:	THOUSAND OAKS
ISSN:	2385-2011
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language DURAL ARTERIOVENOUS-FISTULAS; PERCUTANEOUS EMBOLIZATION; BUTYL CYANOACRYLATE; ONYX; PARAGANGLIOMAS; MALFORMATIONS; OUTCOMES; HEAD Multiple languages Clinical Neurology; Radiology, Nuclear Medicine & Medical Imaging Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/66499