Universität zu Köln

Hachenberg, Jens, Steinkasserer, Lena, Malter, Wolfram, Thangarajah, Fabinshy, Warm, Mathias, Gossmann, Axel, Brod, Markus, Pahmeyer, Caroline and Eichler, Christian (2022). Evaluation of Real-world Data for Breast-MRI BI-RADS IV Lesions. In Vivo, 36 (5). S. 2255 - 2260. ATHENS: INT INST ANTICANCER RESEARCH. ISSN 1791-7549

Full text not available from this repository.

Abstract

Background/Aim: Magnetic resonance imaging (MRI) is an important diagnostic tool in the detection of breast cancer. The Breast Center of the municipal Hospital Holweide, Cologne, annually cares for and treats patients with changes in the breast. A special problem is posed by Breast Imaging-Reporting and Data System (BI-RADS) 4 lesions. If a BI-RADS 4 finding is present, is a vacuum biopsy indicated in every case or, if there is already an indication for surgery due to other findings, can the corresponding finding be removed openly without histological clarification? We require real world data regarding the actual in-center likelihood of a BIRADS 4 lesion to be DCIS (Ductal carcinoma in situ) or invasive disease. Patients and Methods: This is a retrospective study of 1,641 patients who received MRI examination in the radiological department of the municipal hospital Holweide in 2012 and 2013. Each BI-RADS 4 finding (or higher) classified by MRI was compared with the final histological result. Results: 347 MRIs showed BI-RADS 4 findings or higher and 280 (80.7%) cases showed benign histology. In 67 (19.3%) cases, histology showed DCIS or invasive carcinoma. Conclusion: BI-RADS 4 lesions have a low probability of malignancy based on real-world data from this center. If there is already an indication for surgery due to other lesions, the patient can also be offered a simultaneous open biopsy in the context of the already initiated surgical treatment. Each center should know the sensitivity and specificity of the MRI imaging performed and counsel patients based on that.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Hachenberg, Jens UNSPECIFIED UNSPECIFIED UNSPECIFIED Steinkasserer, Lena UNSPECIFIED UNSPECIFIED UNSPECIFIED Malter, Wolfram UNSPECIFIED UNSPECIFIED UNSPECIFIED Thangarajah, Fabinshy UNSPECIFIED UNSPECIFIED UNSPECIFIED Warm, Mathias UNSPECIFIED UNSPECIFIED UNSPECIFIED Gossmann, Axel UNSPECIFIED UNSPECIFIED UNSPECIFIED Brod, Markus UNSPECIFIED UNSPECIFIED UNSPECIFIED Pahmeyer, Caroline UNSPECIFIED UNSPECIFIED UNSPECIFIED Eichler, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-677945
DOI:	10.21873/invivo.12953
Journal or Publication Title:	In Vivo
Volume:	36
Number:	5
Page Range:	S. 2255 - 2260
Date:	2022
Publisher:	INT INST ANTICANCER RESEARCH
Place of Publication:	ATHENS
ISSN:	1791-7549
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language BIOPSY; ACCURACY; PAIN Multiple languages Medicine, Research & Experimental Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/67794