Universität zu Köln

Stolpe, Susanne, Scholz, Christian, Stang, Andreas, Boeger, Carsten, Jung, Bettina, Kowall, Bernd and Blume, Cornelia (2022). High patient unawareness for chronic kidney disease even in later stages - but why is it more frequent in women than in men? Dtsch. Med. Wochenschr., 147 (17). S. E70 - 12. STUTTGART: GEORG THIEME VERLAG KG. ISSN 1439-4413

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Abstract

Introduction Chronic kidney failure (CKD) is as common as diabetes or coronary heart disease in a population aged 40 years and older. Although CKD increases the risk of secondary diseases or premature death, patients with CKD are often unaware of their disease. In a recent analysis of German data, unawareness CKD was higher in women than in men. Methods Baseline data from 2010 of 3,305 CKD patients from German cohort studies and registries were analyzed. Stage 1-4 CKD was defined by eGFR (estimated glomerular filtration rate) and albumin-creatinine ratio according to the KDIGO-guideline. Patient knowledge of CKD was coded according to self-report. The proportion of patients without knowledge of CKD and the sex-specific proportion difference (each with 95 % confidence interval) were calculated according to CKD stages and additional comorbidities (diabetes, hypertension, anemia, and cardiovascular disease). In addition, the prevalence ratio (PR) for not knowing about CKD was estimated for women compared to men crude and adjusted for age and other risk factors. Results Women were less likely than men to know about their CKD in all subgroups studied by age, CKD stage, and comorbidities. The proportion difference for CKD awareness increased with higher CKD stage and was 21 percentage points (7.6; 34.6) at the expense of women in CKD stage 4. Among patients with CKD stage 3b and concomitant grade 2 hypertension, 61 % of women versus 45 % of men were unaware of their disease. The PR for CKD unawareness in women compared with men in the fully adjusted model increased from 1.08 (1.00; 1.16) in CKD stage 3a to 1.75 (1.14; 2.68) in CKD stage 4. Conclusion Despite the presence risk factors that necessitate monitoring of renal function, less than half of patients know they have CKD stage 3b or 4. Women are less likely to be aware of their CKD in all subgroups. Possible causes are gender-related differences in primary health care (gender bias) or in patient-doctor communication.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Stolpe, Susanne UNSPECIFIED UNSPECIFIED UNSPECIFIED Scholz, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Stang, Andreas UNSPECIFIED UNSPECIFIED UNSPECIFIED Boeger, Carsten UNSPECIFIED UNSPECIFIED UNSPECIFIED Jung, Bettina UNSPECIFIED UNSPECIFIED UNSPECIFIED Kowall, Bernd UNSPECIFIED UNSPECIFIED UNSPECIFIED Blume, Cornelia UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-678893
DOI:	10.1055/a-1819-0870
Journal or Publication Title:	Dtsch. Med. Wochenschr.
Volume:	147
Number:	17
Page Range:	S. E70 - 12
Date:	2022
Publisher:	GEORG THIEME VERLAG KG
Place of Publication:	STUTTGART
ISSN:	1439-4413
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language GENDER-DIFFERENCES; BLOOD-PRESSURE; RISK; MANAGEMENT; PHYSICIANS; AWARENESS; FAILURE; CARE; EQUATIONS Multiple languages Medicine, General & Internal Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/67889