Universität zu Köln

Muacevic, Alexander, Eder, Michael Martin, Hofmann, Theresa, Fuerweger, Christoph and Ehret, Felix ORCID: 0000-0001-6177-1755 (2022). Self-Shielding Gyroscopic Radiosurgery-A First Clinical Experience, Case Series, and Dosimetric Comparison. World Neurosurg., 164. S. E420 - 7. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1878-8769

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Abstract

- BACKGROUND: Self-shielding gyroscopic radiosurgery (GRS) represents a technical innovation in the field of stereotactic radiosurgery. GRS does not require a radiation vault and is optimized for radiosurgical treatments. Reports on its usage are limited. We describe the first clinical experience of GRS at our institution to assess the application of GRS in the treatment of cranial tumors. Moreover, we perform a dosimetric comparison to robotic radiosurgery (RRS) with vestibular schwannoma (VS) GRS patients. - METHODS: Patients who were treated with GRS between July and November 2021 were included. Patient, tumor, and dosimetric characteristics were retrospectively summarized and analyzed. - RESULTS: Forty-one patients with 48 intracranial tumors were included. Tumor entities mostly comprised VS, brain metastases, and meningiomas. The median prescription dose and isodose line were 13.5 Gy and 50.0% for benign neoplasia versus 20 Gy and 60.0% for malignant tumors, respectively. The mean planning target volume was 1.5 cubic centimeters. All patients received a single-fraction treatment without encountering any technical setup difficulties. Treatment plan comparisons with RRS revealed comparable plan characteristics, dose gradients, and organs at risk doses. Significant differences were detected concerning the new conformity index and number of monitor units per treatment (both P < 0.01). - CONCLUSIONS: This case series provides more evidence on the usage of self-shielding GRS in the management of cranial tumors. Dosimetric comparisons for VS cases revealed mostly equivalent dosimetric characteristics to RRS. Further clinical and physical analyses for GRS are underway.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Muacevic, Alexander UNSPECIFIED UNSPECIFIED UNSPECIFIED Eder, Michael Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Hofmann, Theresa UNSPECIFIED UNSPECIFIED UNSPECIFIED Fuerweger, Christoph UNSPECIFIED UNSPECIFIED UNSPECIFIED Ehret, Felix UNSPECIFIED orcid.org/0000-0001-6177-1755 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-681705
DOI:	10.1016/j.wneu.2022.04.120
Journal or Publication Title:	World Neurosurg.
Volume:	164
Page Range:	S. E420 - 7
Date:	2022
Publisher:	ELSEVIER SCIENCE INC
Place of Publication:	NEW YORK
ISSN:	1878-8769
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language RADIOTHERAPY; CONFORMITY Multiple languages Clinical Neurology; Surgery Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/68170