Universität zu Köln

Kowoll, Christina M., Klein, Matthias, Salih, Farid ORCID: 0000-0003-1114-3181, Fink, Gereon R. ORCID: 0000-0002-8230-1856, Stetefeld, Henning R., Onur, Oezguer A. and Malter, Michael P. (2022). IGNITE Status Epilepticus Survey: A Nationwide Interrogation about the Current Management of Status Epilepticus in Germany. J. Clin. Med., 11 (5). BASEL: MDPI. ISSN 2077-0383

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Abstract

We aimed to evaluate the current management of status epilepticus (SE) in intensive care units (ICUs) in Germany, depending on the different hospital levels of care and the ICU specialty. We performed a nationwide web-based anonymized survey, including all German ICUs registered with the German Society for Neurointensive and Emergency Care (Deutsche Gesellschaft fur Neurointensiv- und Notfallmedizin; DGNI). The response rate was 83/232 (36%). Continuous EEG monitoring (cEEG) was available in 86% of ICUs. Regular written cEEG reports were obtained in only 50%. Drug management was homogeneous with a general consensus regarding substance order: benzodiazepines-anticonvulsants-sedatives. Thereunder first choice substances were lorazepam (90%), levetiracetam (91%), and propofol (73%). Data suggest that network structures for super-refractory SE are not permeable, as 75% did not transfer SE patients. Our survey provides real world data concerning the current management of SE in Germany. Uniform standards in the implementation of cEEG could help further improve the overall quality. Initial therapy management is standardized. For super-refractory SE, a concentration of highly specialized centers establishing network structures analogous to neurovascular diseases seems desirable to apply rescue therapies with low evidence carefully, ideally collecting data on this rare condition in registries and clinical trials.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Kowoll, Christina M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Klein, Matthias UNSPECIFIED UNSPECIFIED UNSPECIFIED Salih, Farid UNSPECIFIED orcid.org/0000-0003-1114-3181 UNSPECIFIED Fink, Gereon R. UNSPECIFIED orcid.org/0000-0002-8230-1856 UNSPECIFIED Stetefeld, Henning R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Onur, Oezguer A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Malter, Michael P. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-684554
DOI:	10.3390/jcm11051171
Journal or Publication Title:	J. Clin. Med.
Volume:	11
Number:	5
Date:	2022
Publisher:	MDPI
Place of Publication:	BASEL
ISSN:	2077-0383
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CRITICALLY-ILL ADULTS; CONTINUOUS EEG; CONSENSUS STATEMENT; CHILDREN Multiple languages Medicine, General & Internal Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/68455